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Keywords: coagulation
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Articles
Biochem Soc Trans (2016) 44 (1): 35–39.
Published: 09 February 2016
...Tomas L. Lindahl; Sofia Ramström; Niklas Boknäs; Lars Faxälv Platelet-derived polyphosphates (polyP), stored in dense granule and released upon platelet activation, have been claimed to enhance thrombin activation of coagulation factor XI (FXI) and to activate FXII directly. The latter claim...
Articles
Biochem Soc Trans (2016) 44 (1): 18–24.
Published: 09 February 2016
... monomers in length. These linear polymers act at various points in the coagulation and fibrinolytic systems thereby modulating the haemostatic response. Due to its highly anionic nature, polyP lends itself to being a natural activator of the contact system. The contact system functions in multiple pathways...
Articles
Biochem Soc Trans (2013) 41 (1): 273–276.
Published: 29 January 2013
... on tumour biology. Of particular interest is the potential role of extracellular vesicles as orchestrators of common features of the malignant tumour microenvironment, e.g. coagulation activation and angiogenesis. 1 To whom correspondence should be addressed (email Mattias.Belting@med.lu.se...
Articles
Biochem Soc Trans (2007) 35 (3): 555–558.
Published: 22 May 2007
...A. Amour; J. Hutchinson; A.M. Ruiz Avendaño; S. Ratcliffe; E. Alvarez; J. Martin; J.R. Toomey; S. Senger; M. Wolfendale; C. Mooney Coagulation proteases are involved in a highly orchestrated proteolytic cascade which is essential for haemostasis and blood clotting. In particular, the initiator...
Articles
Biochem Soc Trans (2005) 33 (2): 428–432.
Published: 01 April 2005
... a balance between coagulation and fibrinolysis to maintain the integrity of the vasculature, and complex physiological changes are evident during pregnancy which appear to ensure a constant coagulation/fibrinolysis balance. This balance is maintained, at least partly, by an increase in fibrinolytic activity...
Articles
Biochem Soc Trans (2005) 33 (2): 418–422.
Published: 01 April 2005
...K.-E. Eilertsen; B. Østerud The transmembrane glycoprotein TF (tissue factor) plays an essential role in haemostasis as the principal initiator of blood coagulation. In this paper, we describe how the circulating blood cells – monocytes, platelets, neutrophils and their microparticles – co-operate...