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Keywords: co-stimulatory molecule
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Biochem Soc Trans (2007) 35 (5): 1114–1118.
Published: 25 October 2007
... migration, including integrins and chemokines. However, recent studies have highlighted the key role of the T-cell receptor and co-stimulatory molecules in guiding T-cell access to antigenic tissue. Here, we review the experimental evidence for an essential contribution of co-stimulation-mediated molecular...