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Keywords: clathrin
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Biochem Soc Trans (2024) 52 (1): 1–13.
Published: 04 January 2024
... by Portland Press Limited on behalf of the Biochemical Society 2024 cancer caveolae clathrin endocytosis signaling Intersectins (ITSNs) are multi-domain scaffold proteins consisting of Eps15 homology (EH) domains, a coiled-coil (CC) domain, and multiple Src homology 3 (SH3) domains ( Figure...
Biochem Soc Trans (2018) 46 (3): 565–576.
Published: 20 April 2018
... each step, the actin cytoskeleton contributes to all. However, its role can be indirect to the actual molecular events driving endocytosis. Here, we review our understanding of the molecular steps mediating local actin polymerization during the formation of endocytic carriers. Clathrin-mediated...
Biochem Soc Trans (2010) 38 (3): 797–806.
Published: 24 May 2010
...Sebastian Y. Bednarek; Steven K. Backues Two separate families of Arabidopsis dynamin-related proteins, DRP1 and DRP2, have been implicated in clathrin-mediated endocytosis and cell plate maturation during cytokinesis. The present review summarizes the current genetic, biochemical and cell...
Biochem Soc Trans (2010) 38 (1): 181–186.
Published: 19 January 2010
...Arndt Pechstein; Oleg Shupliakov; Volker Haucke During neurotransmitter release, SVs (synaptic vesicles) fuse at the active zone and are recovered predominantly via clathrin-mediated endocytosis at the presynaptic compartment surrounding the site of release, referred to as the periactive zone. Exo...
Biochem Soc Trans (2009) 37 (6): 1355–1358.
Published: 19 November 2009
... via the direct binding of specific endocytosis motifs within the intracellular domains of receptor β 1-3 and γ 2 subunits to the clathrin adaptor protein AP2 (adaptor protein 2). These binding motifs contain major sites of both serine and tyrosine phosphorylation within GABA A Rs...
Biochem Soc Trans (2007) 35 (4): 764–766.
Published: 20 July 2007
...-arrestin is bound to the activated GPCR, it can target the receptor to clathrin-coated pits by interacting with clathrin and adaptor protein 2. Receptors utilizing this pathway are internalized into early endosomes in a dynamin-dependent manner. Sorting follows and at a simplistic level, receptors appear...
Biochem Soc Trans (2006) 34 (1): 68–72.
Published: 20 January 2006
...G.J. Augustine; J.R. Morgan; C.A. Villalba-Galea; S. Jin; K. Prasad; E.M. Lafer The role of clathrin-mediated endocytosis in SV (synaptic vesicle) recycling has been studied by combining molecular biology, physiology and electron microscopy at the squid giant synapse. Procedures that prevent...
Biochem Soc Trans (2005) 33 (6): 1285–1289.
Published: 26 October 2005
...V. Haucke Endocytosis of transmembrane receptors largely occurs via clathrin-coated vesicles that bud from the plasma membrane and deliver their cargo to the endosomal system for recycling or degradation. PIs (phosphoinositides) control the timing and localization of endocytic membrane trafficking...
Biochem Soc Trans (2004) 32 (1): 1–14.
Published: 01 February 2004
...D.J. Owen Clathrin-mediated endocytosis is the major process by which transmembrane proteins are internalized from the cell's limiting membrane into the first compartment of the endosomal system, the early endosome. From here, these transmembrane cargo proteins, which are of widely varying type...