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Keywords: chronic obstructive pulmonary disease (COPD)
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Articles

Overcoming steroid unresponsiveness in airways disease

Ian M. Adcock, Pai-Chien Chou, Andrew Durham, Paul Ford
Journal: Biochemical Society Transactions
Biochem Soc Trans (2009) 37 (4): 824–829.
https://doi.org/10.1042/BST0370824
Published: 22 July 2009
... determined and this may lead to new therapeutic strategies [ 20 ]. 1 To whom correspondence should be addressed (email ian.adcock@imperial.ac.uk ). 17 2 2009 © The Authors Journal compilation © 2009 Biochemical Society 2009 asthma chronic obstructive pulmonary disease (COPD...
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Articles

Inhibition of inducible nitric oxide synthase in respiratory diseases

Christian Hesslinger, Andreas Strub, Rainer Boer, Wolf-Rüdiger Ulrich, Martin D. Lehner, Clemens Braun
Journal: Biochemical Society Transactions
Biochem Soc Trans (2009) 37 (4): 886–891.
https://doi.org/10.1042/BST0370886
Published: 22 July 2009
... correspondence should be addressed (email Christian.Hesslinger@nycomed.com ). 2 Present address: Laboratorios Almirall S.A., Barcelona, Spain. 5 3 2009 © The Authors Journal compilation © 2009 Biochemical Society 2009 asthma chronic obstructive pulmonary disease (COPD) inducible...
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Articles

Array of hope: expression profiling identifies disease biomarkers and mechanism

Soumyaroop Bhattacharya, Thomas J. Mariani
Journal: Biochemical Society Transactions
Biochem Soc Trans (2009) 37 (4): 855–862.
https://doi.org/10.1042/BST0370855
Published: 22 July 2009
... of molecular-targeted therapies. 1 To whom correspondence should be addressed (email tom_mariani@urmc.rochester.edu ). 26 2 2009 © The Authors Journal compilation © 2009 Biochemical Society 2009 biomarker chronic obstructive pulmonary disease (COPD) disease mechanism expression...
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Articles

Twins studies as a model for studies on the interaction between smoking and genetic factors in the development of chronic bronchitis

Magnus Svartengren, Gunnar Engström, Martin Anderson, Jenny Hallberg, Goutham Edula, Maria Gerhardsson de Verdier, Magnus Dahlbäck, Claes M. Lindberg, Kristina Forsman-Semb, Ulf Nihlén, Thomas E. Fehniger
Journal: Biochemical Society Transactions
Biochem Soc Trans (2009) 37 (4): 814–818.
https://doi.org/10.1042/BST0370814
Published: 22 July 2009
... © The Authors Journal compilation © 2009 Biochemical Society 2009 chronic obstructive pulmonary disease (COPD) heritability inflammatory marker multi-slice computed tomography (MSCT) smoking twin COPD (chronic obstructive pulmonary disease) represents an important and increasing...
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Articles

Accelerated lung aging: a novel pathogenic mechanism of chronic obstructive pulmonary disease (COPD)

William MacNee
Journal: Biochemical Society Transactions
Biochem Soc Trans (2009) 37 (4): 819–823.
https://doi.org/10.1042/BST0370819
Published: 22 July 2009
... ], suggesting that aging in this model directly enhances the lung injury produced by cigarette smoke. 1 email wmacnee@staffmail.ed.ac.uk 30 4 2009 © The Authors Journal compilation © 2009 Biochemical Society 2009 aging chronic obstructive pulmonary disease (COPD) emphysema...
View article titled, Accelerated lung aging: a novel pathogenic mechanism of <span class="search-highlight">chronic</span> <span class="search-highlight">obstructive</span> <span class="search-highlight">pulmonary</span> <span class="search-highlight">disease</span> (<span class="search-highlight">COPD</span>)
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Articles

Regulation of cAMP by the p75 neurotrophin receptor: insight into drug design of selective phosphodiesterase inhibitors

B.D. Sachs, K. Akassoglou
Journal: Biochemical Society Transactions
Biochem Soc Trans (2007) 35 (5): 1273–1277.
https://doi.org/10.1042/BST0351273
Published: 25 October 2007
... correspondence should be addressed (email akass@ucsd.edu ). 7 8 2007 © The Authors Journal compilation © 2007 Biochemical Society 2007 axonal regeneration chronic obstructive pulmonary disease (COPD) fibrosis neurotrophin peptide array phosphodiesterase 4A (PDE4A) cAMP...
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Articles

Redox regulation of lung inflammation: role of NADPH oxidase and NF-κB signalling

H. Yao, S.-R. Yang, A. Kode, S. Rajendrasozhan, S. Caito, D. Adenuga, R. Henry, I. Edirisinghe, I. Rahman
Journal: Biochemical Society Transactions
Biochem Soc Trans (2007) 35 (5): 1151–1155.
https://doi.org/10.1042/BST0351151
Published: 25 October 2007
... irfan_rahman@urmc.rochester.edu ). 3 5 2007 © The Authors Journal compilation © 2007 Biochemical Society 2007 chronic obstructive pulmonary disease (COPD) cigarette smoke histone deacetylase (HDAC) Nox nuclear factor-erythroid 2 p45 subunit-related factor 2 (Nrf2) oxidant...
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Articles

Oxidative stress and macrophage function: a failure to resolve the inflammatory response

P. Kirkham
Journal: Biochemical Society Transactions
Biochem Soc Trans (2007) 35 (2): 284–287.
https://doi.org/10.1042/BST0350284
Published: 20 March 2007
... chronic diseases [ 28 ]. 1 email paul.kirkham@novartis.com 25 9 2006 © 2007 The Biochemical Society 2007 chronic obstructive pulmonary disease (COPD) histone deacetylase (HDAC) inflammatory response macrophage oxidative stress reactive oxygen species In the last...
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Articles

Impact of post-translational modifications of proteins on the inflammatory process

K. Ito
Journal: Biochemical Society Transactions
Biochem Soc Trans (2007) 35 (2): 281–283.
https://doi.org/10.1042/BST0350281
Published: 20 March 2007
... 323 23 Irusen E. Matthews J.G. Takahashi A. Barnes P.J. Chung K.F. Adcock I.M. J. Allergy Clin. Immunol. 2002 109 649 657 25 9 2006 © 2007 The Biochemical Society 2007 acetylation chronic obstructive pulmonary disease (COPD...
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Articles

PI 3-kinase inhibition: a therapeutic target for respiratory disease

P.M. Finan, M.J. Thomas
Journal: Biochemical Society Transactions
Biochem Soc Trans (2004) 32 (2): 378–382.
https://doi.org/10.1042/bst0320378
Published: 01 April 2004
...-mail peter.finan@pharma.novartis.com ). PI-3 Kinase in Signalling and Disease, a Biochemical Society Focused Meeting held at Novartis Horsham Research Centre, U.K., 11–12 November 2003 20 January 2004 © 2004 Biochemical Society 2004 asthma chronic obstructive pulmonary disease (COPD...
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