... restore steroid responsiveness in these patients. 1 To whom correspondence should be addressed (email ian.adcock@imperial.ac.uk ). 17 2 2009 © The Authors Journal compilation © 2009 Biochemical Society 2009 asthma chronic obstructive pulmonary disease (COPD...

... inflammation but are ineffective under acute inflammatory conditions. The question whether the anti-inflammatory activity of iNOS inhibition eventually results in a reduction of emphysema induction and airway remodelling has to be tested in long-term smoke models. asthma chronic obstructive pulmonary...

... tom_mariani@urmc.rochester.edu ). 26 2 2009 © The Authors Journal compilation © 2009 Biochemical Society 2009 biomarker chronic obstructive pulmonary disease (COPD) disease mechanism expression profiling lung microarray The completion of genome sequencing of specific organisms...

... The Authors Journal compilation © 2009 Biochemical Society 2009 chronic obstructive pulmonary disease (COPD) heritability inflammatory marker multi-slice computed tomography (MSCT) smoking twin COPD (chronic obstructive pulmonary disease) represents an important and increasing burden...

... ], suggesting that aging in this model directly enhances the lung injury produced by cigarette smoke. 1 email wmacnee@staffmail.ed.ac.uk 30 4 2009 © The Authors Journal compilation © 2009 Biochemical Society 2009 aging chronic obstructive pulmonary disease (COPD) emphysema...

... correspondence should be addressed (email akass@ucsd.edu ). 7 8 2007 © The Authors Journal compilation © 2007 Biochemical Society 2007 axonal regeneration chronic obstructive pulmonary disease (COPD) fibrosis neurotrophin peptide array phosphodiesterase 4A (PDE4A) AD...

... irfan_rahman@urmc.rochester.edu ). 3 5 2007 © The Authors Journal compilation © 2007 Biochemical Society 2007 chronic obstructive pulmonary disease (COPD) cigarette smoke histone deacetylase (HDAC) Nox nuclear factor-erythroid 2 p45 subunit-related factor 2 (Nrf2) oxidant...

... The Biochemical Society 2007 chronic obstructive pulmonary disease (COPD) histone deacetylase (HDAC) inflammatory response macrophage oxidative stress reactive oxygen species 1 email paul.kirkham@novartis.com Regulating the clearance of apoptotic cells can be viewed from two...

... obstructive pulmonary disease (COPD) glucocorticoid histone deacetylase (HDAC) nuclear factor κB (NF-κB) post-translational modification PTM (post-translational modification) is the chemical modification of a protein after its translation, and there are hundreds of different PTMs...

...-mail peter.finan@pharma.novartis.com ). PI-3 Kinase in Signalling and Disease, a Biochemical Society Focused Meeting held at Novartis Horsham Research Centre, U.K., 11–12 November 2003 20 January 2004 © 2004 Biochemical Society 2004 asthma chronic obstructive pulmonary disease (COPD...