... compilation © 2015 Biochemical Society 2015 anaphase-promoting complex chromosome segregation kinetochore microtubule mitosis spindle checkpoint Chromosome bi-orientation, which is the process whereby sister chromatids are attached to dynamic microtubules from opposite spindle poles...

... in Drosophila . Chromosome Segregation and Aneuploidy: An Independent Meeting held at the Royal College of Surgeons, Edinburgh, U.K., 19–23 June 2010. Organized and Edited by Bill Earnshaw (Wellcome Trust Centre for Cell Biology, Edinburgh, U.K.), Kevin Hardwick (Wellcome Trust Centre for Cell...

... pombe suggested that cytokinesis and chromosome segregation are not co-ordinated with each other. However, recent studies indicate that, at least in budding yeast, a checkpoint called NoCut prevents abscission when spindle elongation is impaired, and might delay cytokinesis until all chromosomes...

... as generating genetic diversity, they promote proper chromosome segregation through the establishment of chiasmata. However, crossing over in vegetative cells can potentially result in loss of heterozygosity and chromosome rearrangements, which can be deleterious. Consequently, cells have evolved mechanisms...