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Keywords: chaperone-assisted selective autophagyClose
Barbara Tedesco, Veronica Ferrari, Marta Cozzi, Marta Chierichetti, Elena Casarotto, Paola Pramaggiore, Francesco Mina, Margherita Piccolella, Riccardo Cristofani, Valeria Crippa, Paola Rusmini, Mariarita Galbiati, Angelo Poletti
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (5): 1489–1503.
Published: 16 September 2022
... (MTOC), where aggresomes are assembled [ 15–19 ]. This route, known as chaperone-assisted selective autophagy (CASA) [ 20 , 21 ], is based on misfolded protein recognition by a heteromeric complex of the small heat shock protein B8 (HSPB8) and its obligatory partner Bcl-2-associated athanogene 3 (BAG3...