... events on the centrosome equivalent, the spindle pole body, plays a key role in ensuring that the timing of cell division is coupled to environmental cues. 1 To whom correspondence should be addressed (email ihagan@picr.man.ac.uk ). 7 8 2013 © The Authors Journal compilation © 2013...

... with the centrosome and the microtubule cytoskeleton. The position of the centrosome relative to the NE is of vital importance for many cell functions, such as cell migration and division, and centrosomal dislocation is a frequent phenotype in laminopathic disorders. Also in mitosis, a small group of transmembrane NE...

... in a GTP-dependent process and transmit signals throughout the cell. The orientation of α- and β-subunits creates polar polymers with distinct plus and minus ends [ 34 ]. The minus end of the microtubules associate with the centrosome MTOC (microtubule-organizing centre), which forms the mitotic spindle...

... (anchorage 1)/SYNE (synaptic nuclear envelope protein) homology]-domain family, which function primarily as exclusive outer nuclear membrane scaffolds that associate with the cytoskeleton, the centrosome and the motor protein apparatus. In the present paper, we propose a novel model, which may explain why...