... or EGFP assays. This functional assay is advantageous in providing a positive read-out over a low background and is increasingly used by researchers interested in ON delivery strategies. 8 5 2007 © The Authors Journal compilation © 2007 Biochemical Society 2007 cell-penetrating peptide...

... Reliable method to rapidly identify proteins interacting in vivo with the target RNA [ 36 ] antisense oligonucleotide cell-penetrating peptide (CPP) plasmid delivery small interfering RNA (siRNA) regulation of gene expression transactivator of transcription (Tat) Hence, the real...

... Biochemical Society 2007 cell-penetrating peptide (CPP) drug delivery glypican heparan sulfate proteoglycan (HSPG) protein transduction domain (PTD) syndecan Cationic lipids and polymers, such as PEI (polyethyleneimine), enter cells efficiently and are widely used as transfection agents...

... Society 2007 cell-penetrating peptide (CPP) inflammation nuclear factor κB (NF-κB) protein transduction domain PTDs (protein transduction domains) or CPPs (cell-penetrating peptides) are small peptides which are able to carry much larger molecules such as oligonucleotides, peptides, full...

... and intense enhancement of fluorescence in kidney sections ( Figure 3 A). Moreover, the fluorescence signal in the kidney sections was still detecTable 24 h after i.p. injection. A weaker, but significant, uptake was also observed in spleen and liver sections ( Figure 3 B). cell-penetrating peptide (CPP...

... the nanocarrier is inside the biological target, thus minimizing the interaction with non-target cells. 1 email v.torchilin@neu.edu 20 4 2007 © The Authors Journal compilation © 2007 Biochemical Society 2007 cell-penetrating peptide (CPP) intracellular delivery liposome nanoparticle...

... compilation © 2007 Biochemical Society 2007 Bax-inhibiting peptide (BIP) cell-penetrating peptide (CPP) drug delivery pentapeptide Bax, a 21 kDa protein, is a member of the Bcl-2 family of proteins, which plays a key role in programmed cell death [ 1 , 2 ]. Bax normally resides...

.... 1 To whom correspondence should be addressed (email moulton@avibio.com ). 18 5 2007 © The Authors Journal compilation © 2007 Biochemical Society 2007 cell-penetrating peptide (CPP) Duchenne muscular dystrophy (DMD) exon skipping morpholino poly-arginine toxicity...

...-specific manner. These peptides appear to be able to concentrate in the target tissue, making them particularly efficient delivery vectors for the targeting of drugs, other therapeutic moieties and imaging agents. cell-penetrating peptide (CPP) homing peptide phage display targeted therapy...

...-lymphoma regimens. Peptide therapeutics represent one possible route towards overcoming some of these limitations. 1 email amelnick@aecom.yu.edu 23 4 2007 © The Authors Journal compilation © 2007 Biochemical Society 2007 B-cell lymphoma (Bcl) cell-penetrating peptide (CPP...

.... Takeuchi T. Nakase I. Storm G. Jones A.T. Biochem. J. 2007 403 335 342 30 Al-Taei S. Penning N.A. Simpson J.C. Futaki S. Takeuchi T. Nakase I. Jones A.T. Bioconjugate Chem. 2006 17 90 100 cell-penetrating peptide (CPP) arginine-rich...

... To whom correspondence should be addressed (email blebleu@univ-montp2.fr ). 18 8 2006 © 2007 The Biochemical Society 2007 cell-penetrating peptide (CPP) endocytosis nucleic acid delivery peptide-based delivery splice-correcting oligonucleotide Synthetic ONs (oligonucleotides...

... The Biochemical Society 2007 cell-penetrating peptide (CPP) macromolecular drug delivery monoclonal antibody nanotechnology oligonucleotide-based drug Great strides are being made in the evolution of macromolecular therapeutics. In the future, we can expect further advances based on several...