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Keywords: cell signalling
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Biochem Soc Trans (2014) 42 (5): 1429–1434.
Published: 18 September 2014
... Biochemical Society 2014 ABL1 angiogenesis cell signalling neuropilin-1 oxygen-induced retinopathy paxillin Neuropilin-1 (NRP1) plays a central role in endothelial cells (ECs). Loss of NRP1 in mouse embryos reduces angiogenesis in the brain and spinal cord and leads to embryonic lethality...
Biochem Soc Trans (2014) 42 (1): 103–107.
Published: 23 January 2014
.../by/3.0/ ) which permits unrestricted use, distribution and reproduction in any medium, provided the original work is properly cited. antioxidant response cancer cell signalling degradation drug design ubiquitylation Specific patterns of mono- or poly-ubiquitylation are used by the cell...
Biochem Soc Trans (2013) 41 (5): 1195–1200.
Published: 23 September 2013
... signals, while interconnectivities between pathways lead to an enhanced complexity of regulatory responses that enable sophisticated adaptation. In principle, any cell signalling pathway may be rewired to respond to non-cognate signals by exchanging and recombining their underlying cognate signalling...
Biochem Soc Trans (2012) 40 (1): 133–138.
Published: 19 January 2012
..., and it is becoming increasingly recognized that cellular adaptations result from the quantitative integration of multi-pathway network activities, rather than isolated pathways causing particular phenotypes. Therefore comprehending liver cell signalling in inflammation requires a scientific approach...
Biochem Soc Trans (2011) 39 (5): 1217–1220.
Published: 21 September 2011
... of lipidomics (driven in part by innovations in MS-based analysis), the acceleration of new insights into the role of oxidative protein modifications (particularly to cysteine residues) in modulating cell signalling, and the effects of free radicals on the functions of mitochondria, extracellular matrix...
Biochem Soc Trans (2011) 39 (5): 1221–1225.
Published: 21 September 2011
... dichlorodihydrofluorescein or dihydrorhodamine. 1 email balarama@mcw.edu . 15 7 2011 © The Authors Journal compilation © 2011 Biochemical Society 2011 cell signalling fluorescence mitochondrion reactive nitrogen species (RNS) reactive oxygen species (ROS) redox biology superoxide...
Biochem Soc Trans (2011) 39 (2): 684–687.
Published: 22 March 2011
... of how these proteins contribute to disease is far from complete, the present paper attempts to summarize some of the most important recent developments in this field of research. activating transcription factor 4 (ATF4) acute myeloid leukaemia (AML) cell signalling genome-wide association study...
Biochem Soc Trans (2008) 36 (5): 853–857.
Published: 19 September 2008
...), Eduardo Salido (La Laguna, Tenerife, Spain) and Dimitris Xirodimas (Dundee, U.K.). 1 To whom correspondence should be addressed (email mrodriguez@cicbiogune.es ). 10 3 2008 © The Authors Journal compilation © 2008 Biochemical Society 2008 cell signalling inhibitory κB (IκB...
Biochem Soc Trans (2008) 36 (3): 453–458.
Published: 21 May 2008
.... 1 To whom correspondence should be addressed (email cjefferies@rcsi.ie ). 18 2 2008 © The Authors Journal compilation © 2008 Biochemical Society 2008 antiviral response cell signalling interferon regulatory factor (IRF) Toll-like receptor type I interferon ubiquitination...
Biochem Soc Trans (2007) 35 (2): 211–214.
Published: 20 March 2007
... for more answers. © 2007 The Biochemical Society 2007 cell signalling lysophosphatidic acid phosphoinositide 3-kinase (PI3K) phosphatidylinositol 3,4,5-trisphosphate PI3Ks are a conserved family of lipid kinases that catalyse the phosphorylation of the D3 position of the inositol ring...
Biochem Soc Trans (2004) 32 (6): 1040–1044.
Published: 26 October 2004
... of small G-proteins with GPCRs and GPCR-regulatory proteins may influence GPCR signalling and intracellular trafficking. © 2004 The Biochemical Society 2004 cell signalling endocytosis G-protein-coupled receptor small G-protein trafficking Heterotrimeric GPCRs (G-protein-coupled...
Biochem Soc Trans (2004) 32 (5): 861–864.
Published: 26 October 2004
... of the integration of cell signalling will probably reflect many functions performed by members of the AKAP family. 1 To whom correspondence should be addressed (email craig@pharm.sunysb.edu ). 6 7 2004 © 2004 The Biochemical Society 2004 A-kinase anchoring protein (AKAP) AKAP250 cell...
Biochem Soc Trans (2003) 31 (6): 1243–1247.
Published: 01 December 2003
...-terminal extensions are not necessarily important for the function of the respective signal Key words: aspartic protease, cell signalling, endoplasmic reticulum, protein translocation, signal peptide peptidase. Abbreviations used: ER, endoplasmic reticulum; HCV, hepatitis C virus; HLA, human lymphocyte...
Biochem Soc Trans (2001) 29 (4): 606–612.
Published: 01 August 2001
... interactions cell signalling gap junction inhibitors GJIC, gap-junctional intercellular communication Biochemical Society Transactions (200 I) Volume 29, part 4 24 Sipe, J. D. ( I 994) Crit. Rev. Clin. Lab. Sci. 3 I , 325-354 25 Jimenez. J. L., Guijam, J. I., Orlova, E., Zurdo. J., Dobson, C. M...