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Keywords: cell proliferation
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Articles
Biochem Soc Trans (2022) 50 (2): 921–933.
Published: 31 March 2022
... ( matthew.james.smith@umontreal.ca ) * These authors contributed equally to this work. 28 1 2022 15 3 2022 21 3 2022 © 2022 The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society 2022 cell proliferation G-proteins GTPase oncogenesis RAS tumour...
Articles
Biochem Soc Trans (2021) 49 (5): 1997–2006.
Published: 16 August 2021
... agreement with Max Planck Digital Library. cell proliferation evolution neocortex development neural progenitor cells neurogenesis The neocortex is the largest part of the mammalian cerebral cortex and is the seat of higher cognitive functions, such as thinking and language in human...
Articles
Biochem Soc Trans (2017) 45 (2): 287–295.
Published: 13 April 2017
... article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . bacteria cell proliferation cell wall membranes The cell wall is an almost ubiquitous feature of the domain Bacteria. The major...
Articles
Biochem Soc Trans (2016) 44 (4): 1051–1057.
Published: 15 August 2016
... monophosphates, the poly(A) tail, by poly(A) polymerase. This schematic is highly simplified, and does not depict the interactions between the cleavage factors, nor the full range of proteins that may contribute to cleavage and polyadenylation. cancer cell proliferation gene expression mRNA biogenesis...
Articles
Biochem Soc Trans (2012) 40 (1): 101–107.
Published: 19 January 2012
... in different cellular contexts. This has led to their definition in the control of various cell functions, such as cell proliferation in the thyroid and actin cytoskeleton organization in fibroblasts and lymphocytes. Roles for the glycerophosphoinositols in immune and inflammatory responses are also being...
Articles
Biochem Soc Trans (2011) 39 (5): 1455–1459.
Published: 21 September 2011
... ). 28 6 2011 © The Authors Journal compilation © 2011 Biochemical Society 2011 cell adhesion cell proliferation 20 kDa prostate stromal protein (ps20) prostate cancer tumour microenvironment whey acidic protein four-disulfide core 1 (WFDC1) The WAP family has evolved...
Articles
Biochem Soc Trans (2011) 39 (5): 1461–1465.
Published: 21 September 2011
...Cristina Mazzoni; Claudio Falcone Most of the studies on cell proliferation examine the control of gene expression by specific transcription factors that act on transcriptional initiation. In the last few years, it became evident that mRNA stability/turnover provides an important mechanism for post...
Articles
Biochem Soc Trans (2010) 38 (6): 1598–1601.
Published: 24 November 2010
... of methylation reactions. Myc-induced cap methylation is a major effect of Myc function, being necessary for activated protein synthesis, cell proliferation and cell transformation. Inhibition of cap methylation is synthetic lethal with elevated Myc protein expression, which indicates the potential for cap...
Articles
Biochem Soc Trans (2010) 38 (1): 301–306.
Published: 19 January 2010
... controlling cell proliferation and differentiation. Lamins affect the activity of several transcription factors, such as retinoblastoma protein and c-Fos, and signalling pathways, such as the ERK1/2 (extracellular-signal-regulated kinase 1/2) and Notch pathways, which are key regulators of cell-cycle...
Articles
Biochem Soc Trans (2008) 36 (5): 864–867.
Published: 19 September 2008
...Marc Piechaczyk; Rosa Farràs JunB is a member of the AP-1 (activator protein-1) family of dimeric transcription factors. It exerts a dual action on the cell cycle. It is best known as a cell proliferation inhibitor, a senescence inducer and a tumour suppressor. As for the molecular mechanisms...
Articles
Biochem Soc Trans (2008) 36 (3): 528–530.
Published: 21 May 2008
... Society 2008 cell differentiation cell proliferation mRNA translation Musashi protein neural stem cell Xenopus Musashi exerts translational repression of target mRNAs via a 5′-cap-dependent mechanism in neural stem cells, but paradoxically exerts target mRNA translational activation...
Articles
Biochem Soc Trans (2007) 35 (3): 535–537.
Published: 22 May 2007
... hydrogels via hydrogen-bonding and π–π interactions from the fluorenyl rings. These highly hydrated gels allowed for cell proliferation of chondrocytes in three dimensions [Jayawarna, Ali, Jowitt, Miller, Saiani, Gough and Ulijn (2006) Adv. Mater. 18 , 611–614]. We demonstrated that fibrous architecture...
Articles
Biochem Soc Trans (2007) 35 (2): 391–395.
Published: 20 March 2007
... of the cell cycle. We investigated the effect of quinidine and caesium (Cs + ) on cell proliferation, LDH (lactate dehydrogenase) release, free internal calcium, membrane potential, polyamine concentration, ODC (ornithine decarboxylase) activity and polyamine uptake in C6 glioma cells. The EC 50 for reducing...
Articles
Biochem Soc Trans (2007) 35 (2): 277–280.
Published: 20 March 2007
... using primary T-cells from SHIP1 −/− mice have highlighted a new role for SHIP1 in regulatory T-cell development, but also emphasize that this protein is not required for T-cell proliferation. In support of these results, SHIP1 −/− mice are lymphopenic, suggesting that SHIP1 function in T-cells differs...
Articles
Biochem Soc Trans (2007) 35 (1): 133–135.
Published: 22 January 2007
... differentiation cell proliferation prostate cancer transient receptor potential channel (TRP channel) PC (prostate cancer) is one of the leading threats to men's health. Its early stage depends on androgens for growth and survival, and androgen ablation therapy may at this time be effective in causing...
Articles
Biochem Soc Trans (2004) 32 (4): 581–584.
Published: 01 August 2004
... analysis of Arabidopsis TOR mutants indicates that the plant TOR pathway fulfils the same role in controlling cell growth as its other eukaryotic counterparts. In plants, cell proliferation occurs in meristems, dynamic structures continuously traversed by a flux of cells that divide and grow...
Articles
Biochem Soc Trans (2000) 28 (2): 241–245.
Published: 01 February 2000
... arguments - (a) the decline with age in naive T cell proliferation despite their relatively long telomeres; (b) the preservation of T cell proliferation in Werner's syndrome patients despite their cell lines' proclivity to replicative senescence in vitro ; and (c) the ability of PMA and ionomycin...