... community almost two decades ago and widely used ever since. MTOR is a name recently imposed on the TOR community by database curators and used mainly by newcomers. I argue that MTOR is causing needless confusion in the field, and conclude that one should use the name mTOR. cell growth mammalian target...

... at the crossroad of many signalling pathways integrating the energy status of the cell with signals induced by nutrients and growth factors. The TSC1/2 complex is a critical negative regulator of mTORC1 [mTOR (mammalian target of rapamycin) complex 1], and by that controls anabolic processes to promote cell growth...

... kinase 1 (Atg1/Ulk1) autophagy cell growth Drosophila target of rapamycin (TOR) vacuolar protein sorting 34 (Vps34) The TOR proteins were identified in 1991 by Hall and colleagues as direct targets of an antifungal rapamycin–FKBP (FK506-binding protein) complex, and were shown...

...Thomas Porstmann; Claudio R. Santos; Caroline Lewis; Beatrice Griffiths; Almut Schulze Cell growth requires co-ordinated regulation of processes that provide metabolites for the synthesis of macromolecules such as proteins and membrane lipids. In recent years, a lot of emphasis has been placed...

... 699 27 Bauer D.E. Hatzivassiliou G. Zhao F. Andreadis C. Thompson C.B. Oncogene 2005 24 6314 6322 cell growth human vacuolar protein sorting 34 (hVps34) mammalian target of rapamycin (mTOR) phosphatidylinositol 3-phosphate S6 kinase 1 (S6K1) tuberous...

...G. Patsos; V. Hebbe-Viton; R. San Martin; C. Paraskeva; T. Gallagher; A. Corfield O-glycosylation is thought to play a significant role in the regulation of cell growth. However, only limited information is available, and few specific and selective inhibitors have been found. We have synthesized...

...C. Robaglia; B. Menand; Y. Lei; R. Sormani; M. Nicolaï; C. Gery; E. Teoulé; D. Deprost; C. Meyer The TOR (target of rapamycin) pathway is a phylogenetically conserved transduction system in eukaryotes linking the energy status of the cell to the protein synthesis apparatus and to cell growth...

...L. Martínez-Gac; B. Álvarez; Z. García; M. Marqués; M. Arrizabalaga; A.C. Carrera Cell cycle progression is a tightly controlled process. To initiate cell division, mitogens trigger a number of early signals that promote the G 0 –G 1 transition by inducing cell growth and the activation of G 1...

... Institute, 44 Lincoln's Inn Fields, London WC2A 3PX, U.K. (e-mail Or.Kakhlon@cancer.org.uk ). 19 1 2002 © 2002 Biochemical Society 2002 cell growth labile iron pool FT, ferritin H-FT, heavy FT chain L-FT, light FT chain LIP, labile iron pool AS-ODN, antisense oligodeoxy...