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Keywords: cell differentiation
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Articles
Biochem Soc Trans (2021) 49 (4): 1803–1816.
Published: 26 August 2021
... cancer cells [ 120 , 121 ]. Figure 1. Possible role for differentiation strategies and remaining uncertainties for the application to cancer treatment. cancer cell cell differentiation stem cell therapy The process of carcinogenesis involves a series of changes which...
Articles
Biochem Soc Trans (2021) 49 (2): 805–814.
Published: 30 April 2021
... of haematological malignancies. Figure 1. Haematopoiesis involves the epigenetic silencing of alternate fate genes, reducing multipotency and the self-renewal capacity as cells differentiate. Haematopoietic stem cells (HSC) differentiate to multipotent progenitors (MPP) which in turn differentiate...
Articles
Biochem Soc Trans (2022) 50 (1): 499–511.
Published: 11 January 2021
... patterning cell differentiation homeobox genes human pluripotent stem cells neural crest cells © 2022 The Author(s) 2022 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC...
Articles
Biochem Soc Trans (2019) 47 (4): 1077–1089.
Published: 27 June 2019
...-selection. 7 3 2019 5 6 2019 6 6 2019 © 2019 The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society 2019 cell differentiation developmental biology T cells A key attribute of T cell immunity is the expression of a distinct T cell...
Articles
Biochem Soc Trans (2019) 47 (3): 875–885.
Published: 17 June 2019
... their catalytic and non-catalytic roles carry out myriad functions linked to early developmental processes. cell differentiation epigenetics epigenomics methylation model organisms pluripotency Ten-eleven translocation (TET) methylcytosine dioxygenases were first described when TET1...
Articles
Biochem Soc Trans (2018) 46 (5): 1083–1091.
Published: 21 September 2018
.... , Leuckx , G. , Sakano , D. , Seymour , P.A. , Mattsson , C.L. , Rautio , L. et al. ( 2018 ) Inhibition of Cdk5 promotes β-cell differentiation from ductal progenitors . Diabetes 67 , 58 – 70 10.2337/db16-1587 58 Kim , S.Y. , Lee , J.H. , Merrins , M.J...
Articles
Biochem Soc Trans (2008) 36 (3): 528–530.
Published: 21 May 2008
... Society 2008 cell differentiation cell proliferation mRNA translation Musashi protein neural stem cell Xenopus Musashi exerts translational repression of target mRNAs via a 5′-cap-dependent mechanism in neural stem cells, but paradoxically exerts target mRNA translational activation...
Articles
Biochem Soc Trans (2007) 35 (1): 133–135.
Published: 22 January 2007
...N. Prevarskaya; M. Flourakis; G. Bidaux; S. Thebault; R. Skryma A major clinical problem with PC (prostate cancer) is the cell's ability to survive and proliferate upon androgen withdrawal. Indeed, deregulated cell differentiation and proliferation, together with the suppression of apoptosis...
Articles
Biochem Soc Trans (2006) 34 (6): 1133–1137.
Published: 25 October 2006
... remain roughly constant as cells differentiate, despite large changes in the numbers of active polymerases and nucleoplasmic volumes. Figure 1 Model for a polymerase II factory and genome structure in a HeLa cell DNA is coiled around the histone octamer, and runs of nucleosomes form a zigzagging...