.../TNF superfamily C1Ql cell adhesion cell signaling pleiotropy synapse homeostasis The complement 1q (C1q)/tumor necrosis factor (TNF) (C1q/TNF) superfamily may be one of the most increasingly recognized groups of proteins that interconnects all physiological systems [ 1 ]. Their diverse...

...Giulia Mana; Donatella Valdembri; Guido Serini Spatiotemporal control of integrin-mediated cell adhesion to the extracellular matrix (ECM) is critical for physiological and pathological events in multicellular organisms, such as embryonic development, angiogenesis, platelet aggregation, leukocytes...

...Lilian Schimmel; Emma Gordon Endothelial cell–cell adhesion within the wall of the vasculature controls a range of physiological processes, such as growth, integrity and barrier function. The adhesive properties of endothelial cells are tightly controlled by a complex cascade of signals transmitted...

... work into the function of APPL1 in cell migration and adhesion. Correspondence: Donna J. Webb ( donna.webb@vanderbilt.edu ) 15 12 2016 17 3 2017 22 3 2017 © 2017 The Author(s); published by Portland Press Limited on behalf of the Biochemical Society 2017 cell adhesion...

... Attribution License 4.0 (CC BY) . bacterial adhesion cell adhesion host–microbe interactions microbiology Bacteria have evolved an abundance of mechanisms to engage with host cells, and manipulate their cellular signaling programmes to facilitate colonization. Most, if not all...

... summarize the current knowledge on kinesin functions in cell migration. 1 To whom correspondence should be addressed (email anne@mechanochemistry.org ) . 16 10 2014 © The Authors Journal compilation © 2015 Biochemical Society 2015 cell adhesion cell migration force generation...

... and functional characterization of ILK and the long-standing debate regarding its reported kinase activity. 1 To whom correspondence should be addressed (email wickstroem@age.mpg.de ). 23 4 2013 © The Authors Journal compilation © 2013 Biochemical Society 2013 actin cell adhesion...

... that was secreted by fetal urogenital sinus mesenchymal cells. Purified ps20 exhibited several activities that centre on cell adhesion, migration and proliferation. The WFDC1 gene was cloned, contained seven exons, and was mapped to chromosome 16q24, suggesting that it may function as a tumour suppressor; however...

... as associated with certain types of cancer. However, the mechanistic role of this form of glycosylation in many of these instances is unclear. Here we describe how one glycosyltransferase responsible for initiating mucin-type O-glycosylation (PGANT3), specifically modulates integrin-mediated cell adhesion...

... in the vicinity of the synaptic contact. Indeed, members of the neuroligin [ 1 , 2 ], SynCAM (synaptic cell adhesion molecule) [ 3 ], NGL (netrin-G ligand) [ 4 ], or LRRTM (leucine-rich repeat transmembrane) [ 5 ] families of adhesion proteins can locally induce postsynaptic differentiation. This property...

... to the homotypically adhering κ and μ receptors J. Biol. Chem. 1997 272 7264 7277 11 Gebbink M.F. Zondag G.C. Wubbolts R.W. Beijersbergen R.L. van Etten I. Moolenaar W.H. Cell–cell adhesion mediated by a receptor-like protein tyrosine phosphatase J. Biol. Chem. 1993 268 16101...

... bonds. The cumulative results demonstrate that cadherins adhere via a multistage binding mechanism that involves multiple extracellular domains. In kinetic measurements of cell adhesion, cell pairs first form a low-probability-binding state with fast kinetics. This is followed by a lag and a slow...

... in cell–cell contact formation. Cadherins are calcium-dependent cell adhesion molecules whose extracellular regions mediate homotypic cell–cell adhesion. The classical cadherins are found in adherens junctions, cell–cell contact structures that are associated with the actin cytoskeleton [ 1 , 2...

...Gethin Rh. Owen; Devrim Acehan; K.D. Derr; William J. Rice; David L. Stokes Desmosomes are a complex assembly of protein molecules that form at the cell surface and mediate cell–cell adhesion. Much is known about the composition of desmosomes and there is an established consensus for the location...

...Asoka Banno; Mark H. Ginsberg Agonist stimulation of integrin receptors, composed of transmembrane α and β subunits, leads cells to regulate integrin affinity (‘activation’), a process that controls cell adhesion and migration, and extracellular matrix assembly. A final step in integrin activation...

... in susceptible areas of the artery wall. 1 To whom correspondence should be addressed (email chlawson@rvc.ac.uk ). 20 12 2006 © 2007 Biochemical Society 2007 atherosclerosis cell adhesion chylomicron remnant dietary fat monocyte reactive oxygen species It is well...

... © 2004 The Biochemical Society 2004 adherens junction cell adhesion cell polarity Crumbs homologue 1 (CRB1) Leber congenital amaurosis retinitis pigmentosa The human CRB1 protein is a single transmembrane protein with a large extracellular part, containing three laminin G...

... of force to focal adhesions results in the formation of fibrillar adhesions and reorganization of the extracellular matrix. The formation of these adhesions depends on actomyosin contractility and matrix pliability. Introduction Cell adhesion to the ECM (extracellular matrix) plays key roles...

... Molecular Environment of Integrins: a Biochemical Society Focused Meeting held at Chancellors Conference Centre, University of Manchester, 1–3 December 2003 3 December 2003 © 2004 Biochemical Society 2004 cell adhesion FERM domain integrin PTB domain talin Abbreviations...

...T. Chavakis; S. M. Kanse; A. E. May; K. T. Preissner Vascular cell adhesion and migration, proliferation or differentiation are cellular responses that are induced by haemostatic factors of the urokinase/plasminogen activation complex, but the respective underlying mechanisms are largely undefined...