... 7 2023 18 9 2023 20 9 2023 © 2023 The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society 2023 cell adhesion ion channels mechanotransduction PIEZO channels Cells utilize an elaborate mechanosensing program to gauge the physical...

... 25 5 2023 19 6 2023 © 2023 The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society 2023 cadherins cell adhesion collective cell migration Cell migration is fundamental to many key events during embryonic development such as gastrulation...

...Claudia Owczarek; Yassmin Elmasry; Maddy Parsons Coxsackievirus and adenovirus receptor (CAR) is a transmembrane cell–cell adhesion receptor that forms homodimers across junctions and plays a key role in mediating epithelial barrier integrity. CAR can also heterodimerise with receptors...

.../TNF superfamily C1Ql cell adhesion cell signaling pleiotropy synapse homeostasis Since adipose tissue is the largest endocrine organ, many C1q/TNF adipokines are involved in endocrine regulation [ 4 , 43 , 44 ]; however, only a few studies associate C1QLs with endocrine regulation...

...Giulia Mana; Donatella Valdembri; Guido Serini Spatiotemporal control of integrin-mediated cell adhesion to the extracellular matrix (ECM) is critical for physiological and pathological events in multicellular organisms, such as embryonic development, angiogenesis, platelet aggregation, leukocytes...

...Lilian Schimmel; Emma Gordon Endothelial cell–cell adhesion within the wall of the vasculature controls a range of physiological processes, such as growth, integrity and barrier function. The adhesive properties of endothelial cells are tightly controlled by a complex cascade of signals transmitted...

... by Portland Press Limited on behalf of the Biochemical Society 2017 cell adhesion cell migration endosomal sorting protein kinase B Rab5 trafficking APPL1 integrates signaling cross-talk via multiple domains that mediate protein and lipid interactions [ 3 , 4 ]. The N-terminal BAR (Bin...

... 2016 10 8 2016 23 8 2016 © 2016 The Author(s) 2016 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . bacterial adhesion cell adhesion host...

... summarize the current knowledge on kinesin functions in cell migration. 1 To whom correspondence should be addressed (email anne@mechanochemistry.org ) . 16 10 2014 © The Authors Journal compilation © 2015 Biochemical Society 2015 cell adhesion cell migration force generation...

... correspondence should be addressed (email wickstroem@age.mpg.de ). 23 4 2013 © The Authors Journal compilation © 2013 Biochemical Society 2013 actin cell adhesion extracellular matrix integrin-linked kinase (ILK) pseudokinase signalling In order to establish and maintain...

... that was secreted by fetal urogenital sinus mesenchymal cells. Purified ps20 exhibited several activities that centre on cell adhesion, migration and proliferation. The WFDC1 gene was cloned, contained seven exons, and was mapped to chromosome 16q24, suggesting that it may function as a tumour suppressor; however...

... as associated with certain types of cancer. However, the mechanistic role of this form of glycosylation in many of these instances is unclear. Here we describe how one glycosyltransferase responsible for initiating mucin-type O-glycosylation (PGANT3), specifically modulates integrin-mediated cell adhesion...

... Science 1997 277 1511 1515 7 Hirao K. Hata Y. Ide N. Takeuchi M. Irie M. Yao I. Deguchi M. Toyoda A. Südhof T.C. Takai Y. A novel multiple PDZ domain-containing molecule interacting with N-methyl-D-aspartate receptors and neuronal cell adhesion...

... of this phosphatase can be influenced by cell–cell spacings. 1 To whom correspondence should be addressed (email Yvonne@strubi.ox.ac.uk ). 11 1 2008 © The Authors Journal compilation © 2008 Biochemical Society 2008 cell adhesion extracellular complex homodimer protein crystallography...

... bonds. The cumulative results demonstrate that cadherins adhere via a multistage binding mechanism that involves multiple extracellular domains. In kinetic measurements of cell adhesion, cell pairs first form a low-probability-binding state with fast kinetics. This is followed by a lag and a slow...

... catenin cell adhesion Cadherins are calcium-dependent cell adhesion molecules whose extracellular regions mediate homotypic cell–cell adhesion. The classical cadherins are found in adherens junctions, cell–cell contact structures that are associated with the actin cytoskeleton [ 1 , 2 ]. The co...

...Gethin Rh. Owen; Devrim Acehan; K.D. Derr; William J. Rice; David L. Stokes Desmosomes are a complex assembly of protein molecules that form at the cell surface and mediate cell–cell adhesion. Much is known about the composition of desmosomes and there is an established consensus for the location...

...Asoka Banno; Mark H. Ginsberg Agonist stimulation of integrin receptors, composed of transmembrane α and β subunits, leads cells to regulate integrin affinity (‘activation’), a process that controls cell adhesion and migration, and extracellular matrix assembly. A final step in integrin activation...

... in susceptible areas of the artery wall. 1 To whom correspondence should be addressed (email chlawson@rvc.ac.uk ). 20 12 2006 © 2007 Biochemical Society 2007 atherosclerosis cell adhesion chylomicron remnant dietary fat monocyte reactive oxygen species It is well...

... of a therapy for the retinal degenerations caused by mutations in CRB1 . 1 To whom correspondence should be addressed (email j.wijnholds@ioi.knaw.nl ). 6 7 2004 © 2004 The Biochemical Society 2004 adherens junction cell adhesion cell polarity Crumbs homologue 1 (CRB1) Leber...

... matrix. The formation of these adhesions depends on actomyosin contractility and matrix pliability. Introduction Cell adhesion to the ECM (extracellular matrix) plays key roles in the assembly of cells into functional multicellular organisms. At the same time, such adhesions are involved...

... Molecular Environment of Integrins: a Biochemical Society Focused Meeting held at Chancellors Conference Centre, University of Manchester, 1–3 December 2003 3 December 2003 © 2004 Biochemical Society 2004 cell adhesion FERM domain integrin PTB domain talin Abbreviations...

...T. Chavakis; S. M. Kanse; A. E. May; K. T. Preissner Vascular cell adhesion and migration, proliferation or differentiation are cellular responses that are induced by haemostatic factors of the urokinase/plasminogen activation complex, but the respective underlying mechanisms are largely undefined...