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Keywords: cell adhesion
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Articles
Biochem Soc Trans (2020) 48 (1): 83–93.
Published: 17 February 2020
...Giulia Mana; Donatella Valdembri; Guido Serini Spatiotemporal control of integrin-mediated cell adhesion to the extracellular matrix (ECM) is critical for physiological and pathological events in multicellular organisms, such as embryonic development, angiogenesis, platelet aggregation, leukocytes...
Articles
Biochem Soc Trans (2018) 46 (6): 1673–1680.
Published: 04 December 2018
...Lilian Schimmel; Emma Gordon Endothelial cell–cell adhesion within the wall of the vasculature controls a range of physiological processes, such as growth, integrity and barrier function. The adhesive properties of endothelial cells are tightly controlled by a complex cascade of signals transmitted...
Articles
Biochem Soc Trans (2017) 45 (3): 771–779.
Published: 15 June 2017
... work into the function of APPL1 in cell migration and adhesion. Correspondence: Donna J. Webb ( donna.webb@vanderbilt.edu ) 15 12 2016 17 3 2017 22 3 2017 © 2017 The Author(s); published by Portland Press Limited on behalf of the Biochemical Society 2017 cell adhesion...
Articles
Biochem Soc Trans (2016) 44 (6): 1571–1580.
Published: 02 December 2016
... Attribution License 4.0 (CC BY) . bacterial adhesion cell adhesion host–microbe interactions microbiology Bacteria have evolved an abundance of mechanisms to engage with host cells, and manipulate their cellular signaling programmes to facilitate colonization. Most, if not all...
Articles
Biochem Soc Trans (2015) 43 (1): 79–83.
Published: 26 January 2015
... summarize the current knowledge on kinesin functions in cell migration. 1 To whom correspondence should be addressed (email anne@mechanochemistry.org ) . 16 10 2014 © The Authors Journal compilation © 2015 Biochemical Society 2015 cell adhesion cell migration force generation...
Articles
Biochem Soc Trans (2013) 41 (4): 995–1001.
Published: 18 July 2013
... The Authors Journal compilation © 2013 Biochemical Society 2013 actin cell adhesion extracellular matrix integrin-linked kinase (ILK) pseudokinase signalling In order to establish and maintain structural organization and proper function of the tissue, cells need to sense and process...
Articles
Biochem Soc Trans (2011) 39 (5): 1455–1459.
Published: 21 September 2011
... that was secreted by fetal urogenital sinus mesenchymal cells. Purified ps20 exhibited several activities that centre on cell adhesion, migration and proliferation. The WFDC1 gene was cloned, contained seven exons, and was mapped to chromosome 16q24, suggesting that it may function as a tumour suppressor; however...
Articles
Biochem Soc Trans (2011) 39 (1): 378–382.
Published: 19 January 2011
... as associated with certain types of cancer. However, the mechanistic role of this form of glycosylation in many of these instances is unclear. Here we describe how one glycosyltransferase responsible for initiating mucin-type O-glycosylation (PGANT3), specifically modulates integrin-mediated cell adhesion...
Articles
Biochem Soc Trans (2010) 38 (2): 511–515.
Published: 22 March 2010
... (synaptic cell adhesion molecule) [ 3 ], NGL (netrin-G ligand) [ 4 ], or LRRTM (leucine-rich repeat transmembrane) [ 5 ] families of adhesion proteins can locally induce postsynaptic differentiation. This property indicates that the positioning of these proteins on the nascent postsynaptic membrane...
Articles
Biochem Soc Trans (2008) 36 (2): 167–172.
Published: 20 March 2008
.... Moolenaar W.H. Cell–cell adhesion mediated by a receptor-like protein tyrosine phosphatase J. Biol. Chem. 1993 268 16101 16104 12 Sap J. Jiang Y.P. Friedlander D. Grumet M. Schlessinger J. Receptor tyrosine phosphatase R-PTP-κ mediates homophilic binding Mol. Cell Biol...
Articles
Biochem Soc Trans (2008) 36 (2): 213–220.
Published: 20 March 2008
... bonds. The cumulative results demonstrate that cadherins adhere via a multistage binding mechanism that involves multiple extracellular domains. In kinetic measurements of cell adhesion, cell pairs first form a low-probability-binding state with fast kinetics. This is followed by a lag and a slow...
Articles
Biochem Soc Trans (2008) 36 (2): 141–147.
Published: 20 March 2008
... catenin cell adhesion Cadherins are calcium-dependent cell adhesion molecules whose extracellular regions mediate homotypic cell–cell adhesion. The classical cadherins are found in adherens junctions, cell–cell contact structures that are associated with the actin cytoskeleton [ 1 , 2 ]. The co...
Articles
Biochem Soc Trans (2008) 36 (2): 173–179.
Published: 20 March 2008
...Gethin Rh. Owen; Devrim Acehan; K.D. Derr; William J. Rice; David L. Stokes Desmosomes are a complex assembly of protein molecules that form at the cell surface and mediate cell–cell adhesion. Much is known about the composition of desmosomes and there is an established consensus for the location...
Articles
Biochem Soc Trans (2008) 36 (2): 229–234.
Published: 20 March 2008
...Asoka Banno; Mark H. Ginsberg Agonist stimulation of integrin receptors, composed of transmembrane α and β subunits, leads cells to regulate integrin affinity (‘activation’), a process that controls cell adhesion and migration, and extracellular matrix assembly. A final step in integrin activation...
Articles
Biochem Soc Trans (2007) 35 (3): 464–465.
Published: 22 May 2007
... in susceptible areas of the artery wall. 1 To whom correspondence should be addressed (email chlawson@rvc.ac.uk ). 20 12 2006 © 2007 Biochemical Society 2007 atherosclerosis cell adhesion chylomicron remnant dietary fat monocyte reactive oxygen species It is well...
Articles
Biochem Soc Trans (2004) 32 (5): 828–830.
Published: 26 October 2004
... and the Drosophila homologue Crumbs. In the present study, we review the current knowledge on Crumbs and its vertebrate homologues, their function in cell polarity and their pathogenicity in retinal degeneration. © 2004 The Biochemical Society 2004 adherens junction cell adhesion cell polarity Crumbs...
Articles
Biochem Soc Trans (2004) 32 (3): 416–420.
Published: 01 June 2004
... Society 2004 cell adhesion fibrillar adhesion focal adhesion focal complex Abbreviations used: ECM, extracellular matrix; ESEM, environmental scanning electron microscopy; FA, focal adhesion; FB, fibrillar adhesion; FX, focal complex; GFP, green fluorescent protein. 416 Biochemical...
Articles
Biochem Soc Trans (2004) 32 (3): 434–437.
Published: 01 June 2004
... Molecular Environment of Integrins: a Biochemical Society Focused Meeting held at Chancellors Conference Centre, University of Manchester, 1–3 December 2003 3 December 2003 © 2004 Biochemical Society 2004 cell adhesion FERM domain integrin PTB domain talin Abbreviations...
Articles
Biochem Soc Trans (2002) 30 (2): 168–173.
Published: 01 April 2002
...T. Chavakis; S. M. Kanse; A. E. May; K. T. Preissner Vascular cell adhesion and migration, proliferation or differentiation are cellular responses that are induced by haemostatic factors of the urokinase/plasminogen activation complex, but the respective underlying mechanisms are largely undefined...