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Keywords: cartilage degradation
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Biochem Soc Trans (2002) 30 (6): 886–889.
Published: 01 November 2002
... of the protein kinase, PKR. PACT and PKR are upstream components of a number of signal transduction and gene transcription pathways used by pro-inflammatory cytokines. We have investigated the role of PACT and PKR in articular cartilage degradation using cytokine treatment of bovine primary chondrocytes...