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Keywords: cardiomyocyte
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Biochem Soc Trans (2024) 52 (1): 41–53.
Published: 22 February 2024
...Kobina Essandoh; James P. Teuber; Matthew J. Brody Despite the well-established functions of protein palmitoylation in fundamental cellular processes, the roles of this reversible post-translational lipid modification in cardiomyocyte biology remain poorly studied. Palmitoylation is catalyzed...
Biochem Soc Trans (2019) 47 (5): 1341–1353.
Published: 11 October 2019
...Dario Diviani; Halima Osman; Marion Delaunay; Simon Kaiser Cardiac stress initiates a pathological remodeling process that is associated with cardiomyocyte loss and fibrosis that ultimately leads to heart failure. In the injured heart, a pathologically elevated synthesis of reactive oxygen species...
Biochem Soc Trans (2010) 38 (4): 1037–1045.
Published: 26 July 2010
...Emily Dick; Divya Rajamohan; Jonathon Ronksley; Chris Denning Functional cardiomyocytes can now be derived routinely from hPSCs (human pluripotent stem cells), which collectively include embryonic and induced pluripotent stem cells. This technology presents new opportunities to develop...
Biochem Soc Trans (2007) 35 (5): 927–930.
Published: 25 October 2007
... extrusion, in excitable cells, such as cardiomyocytes, PMCA has been shown to play only a minor role in calcium homoeostasis compared with the NCX (sodium/calcium exchanger), another system of calcium extrusion. However, increasing evidence points to an important role for PMCA in signal transduction...
Biochem Soc Trans (2006) 34 (4): 510–511.
Published: 21 July 2006
...M. Mongillo; M. Zaccolo β-Adrenergic signalling mediates the positive inotropic effect of catecholamines on cardiomyocytes, mainly through cAMP generation and subsequent activation of PKA (protein kinase A). Given the large diversity of PKA targets within cardiac cells, a precisely regulated...