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Keywords: calmodulin
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Biochem Soc Trans (2012) 40 (4): 653–655.
Published: 20 July 2012
... for the spreading of tau pathology in these neurodegenerative disorders. 1 To whom correspondence should be addressed (email javila@cbm.uam.es ). 12 1 2012 © The Authors Journal compilation © 2012 Biochemical Society 2012 calmodulin extracellular tau tau secretion ventral dentate...
Biochem Soc Trans (2011) 39 (2): 694–699.
Published: 22 March 2011
...–cell adhesion, cytokinesis and apoptosis. These processes rely on protein–protein interactions, and understanding these (and how they influence one another) is critical in determining how the IQGAPs function. A key group of interactions is with calmodulin and the structurally related proteins myosin...
Biochem Soc Trans (2007) 35 (5): 919–922.
Published: 25 October 2007
... versatility among PMCA isoforms, with specific pumps being essential for cochlear hair cell function, sperm motility, feedback signalling in the heart and pre- and post-synaptic Ca 2+ regulation in neurons. The functional versatility of PMCAs is due to differences in their regulation by CaM (calmodulin...
Biochem Soc Trans (2006) 34 (4): 480–483.
Published: 21 July 2006
..., can sequester calmodulin for its own regulatory purposes. These devices are a sampling of the multiple layers of organization that are in place – even in a simple cell – to ensure faithful and economical communication of the cAMP message. 1 To whom correspondence should be addressed (email...
Biochem Soc Trans (2006) 34 (3): 381–384.
Published: 22 May 2006
... different effects on the distribution of an abundant and important calcium target – calmodulin. Short calcium responses trigger calmodulin translocation into the secretory granule region of the acinar cells, whereas more substantial transients induce nuclear transport of calmodulin and oscillations...
Biochem Soc Trans (2005) 33 (6): 1319–1322.
Published: 26 October 2005
... adenylate cyclase A-kinase anchoring protein (AKAP) calmodulin capacitative Ca 2+ entry (CCE) cyclic nucleotide-gated channel (CNG channel) lipid raft Membrane-bound AC isoforms are large proteins of approx. 120–140 kDa that share a common secondary structure comprising an intracellular N...
Biochem Soc Trans (2004) 32 (5): 868–870.
Published: 26 October 2004
... and 3) and group III (4, 6–8) mGluRs. In the present study, we used a Y2H (yeast two hybrid) screen to identify proteins that interact with the C-terminal intracellular tail of mGluR3. Prominent among the candidate receptor interacting proteins was calmodulin, a Ca 2+ sensor known to bind identifiable...
Biochem Soc Trans (2003) 31 (5): 912–915.
Published: 01 October 2003
... April 2003 © 2003 Biochemical Society 2003 adenylate cyclase calmodulin calcium cAMP-dependent protein kinase caveolae phosphodiesterase Abbreviations used: AC1, AC2, AC3, etc., adenylate cyclase types 1, 2, 3, etc; CCE, capacitative Ca 2+ entry; [Ca 2+ ] i , intracellular...
Biochem Soc Trans (2003) 31 (3): 502–505.
Published: 01 June 2003
... binding of calmodulin (CaM) at elevated intracellular Ca 2+ levels to produce NO as part of a number of cell signalling pathways. CaM binds to the linker region between the two domains and activates the enzyme by inducing intramolecular electron transfer. Protein-engineering experiments have shown...