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Keywords: brain function
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J. Striessnig, A. Koschak, M.J. Sinnegger-Brauns, A. Hetzenauer, N.K. Nguyen, P. Busquet, G. Pelster, N. Singewald
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2006) 34 (5): 903–909.
Published: 25 October 2006
.... In the brain, LTCCs control synaptic plasticity in neurons, and DHP (dihydropyridine) LTCC blockers such as nifedipine modulate brain function (such as fear memory extinction and depression-like behaviour). Voltage-sensitive Ca 2+ channels Ca v 1.2 and Ca v 1.3 are the predominant brain LTCCs. As DHPs...
