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Keywords: bone morphogenetic protein
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Biochem Soc Trans (2017) 45 (1): 173–181.
Published: 15 February 2017
...Georg Sedlmeier; Jonathan P. Sleeman Given its importance in development and homeostasis, bone morphogenetic protein (BMP) signaling is tightly regulated at the extra- and intracellular level. The extracellular matrix (ECM) was initially thought to act as a passive mechanical barrier...
Biochem Soc Trans (2016) 44 (4): 1142–1149.
Published: 15 August 2016
... in actively proliferating endothelial cells (ECs). ALK1 has been shown to play a pivotal role in regulating angiogenesis by binding to bone morphogenetic protein (BMP)9 and 10. Two main pharmacological inhibitors, an ALK1-Fc fusion protein (Dalantercept/ACE-041) and a fully human antibody against...
Biochem Soc Trans (2000) 28 (4): 362–368.
Published: 01 August 2000
...R. C. Spiro; L.-S. Liu; M. A. Heidaran; A. Y. Thompson; C. K. Ng; J. Pohl; J. W. Poser Growth and differentiation factor-5 (GDF-5) is a divergent member of the transforming growth factor-β/bone morphogenetic protein (BMP) superfamily that is required for proper skeletal patterning and development...