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Biochem Soc Trans (2020) 48 (5): 2295–2305.
Published: 29 October 2020
...Jiawei Zhang; Dandan Li; Rui Zhang; Peng Gao; Rongxue Peng; Jinming Li The role of miR-21 in the pathogenesis of various liver diseases, together with the possibility of detecting microRNA in the circulation, makes miR-21 a potential biomarker for noninvasive detection. In this review, we summarize...
Biochem Soc Trans (2019) 47 (2): 725–732.
Published: 08 March 2019
... processes. biomarkers cancer cannibalism cell-in-cell entosis p53 Cell-in-cell (CIC) is a term used in histopathology to describe a phenomenon in which one whole cell can be detected inside another cell [ 1 , 2 ]. The inside cell is often rounded up, usually alive, and resides inside...
Biochem Soc Trans (2018) 46 (6): 1517–1527.
Published: 12 November 2018
... are able of up-taking proteins and genetic material present in the bloodstream. Platelets are like ‘sentinels’ of the disease state. The evaluation of proteomics and transcriptomics signature of platelets and platelet-derived microparticles could represent a new strategy for the development of biomarkers...
Biochem Soc Trans (2018) 46 (5): 1073–1082.
Published: 21 September 2018
... are able to transfer drug resistance when incubated with non-resistant breast cancer cells in vitro [ 31 ]. The presence of EVs in all biological fluids, along with their association with multiple diseases, make them attractive candidates as biomarkers. Their contents reflect their parent cell...
Biochem Soc Trans (2018) 46 (3): 547–553.
Published: 17 April 2018
... with the disease. There are currently no known biomarkers for the disease, largely due to the lack of knowledge surrounding the eitopathogenesis of CFS/ME. Numerous studies have been conducted in an attempt to identify potential biomarkers for the disease. This mini-review offers a brief summary of current...
Biochem Soc Trans (2017) 45 (4): 953–962.
Published: 07 July 2017
... of the Biochemical Society 2017 biomarkers disease gene expression inflammation lncRNA transcriptional regulation The ‘noncoding revolution’ [ 1 ] has reformed our understanding of how the eukaryotic genomic code is arranged, regulated and transcribed. Simply defined as the transcribed yet...
Biochem Soc Trans (2017) 45 (4): 905–911.
Published: 03 July 2017
... 2017 1 6 2017 © 2017 The Author(s); published by Portland Press Limited on behalf of the Biochemical Society 2017 biomarkers cytokines exercise oncology immune response physical training physiology Over the past 25 years, the field of clinical oncology has experienced...
Biochem Soc Trans (2017) 45 (1): 207–212.
Published: 15 February 2017
... for the development of PD-related biomarkers. In conclusion, in addition to being a confirmed therapeutic target for PD, emerging evidence is pointing to LRRK2 as a PD biomarker. This development makes for a welcome addition in the list of potential PD biomarkers under evaluation. However, significant steps remain...