... Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . Alzheimer's disease amyloid beta amyloid precursor protein bioenergetics γ-secretase mitochondria Amyloid beta (Aβ) plaques are a hallmark pathology...

... by Portland Press Limited on behalf of the Biochemical Society 2023 bioenergetics central nervous system insulin resistance metabolism neuromodulation type 2 diabetes Insulin is a peptide best known by being produced by β-cells of the pancreatic islets in response to elevated blood glucose...

... on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . bioenergetics ischaemia-reperfusion injury membrane potential mitochondria reactive oxygen species thermodynamics The operation of a biological system is like the operation...

... of Imperial College London in an all-inclusive Read & Publish pilot with Portland Press and the Biochemical Society under a transformative agreement with JISC. bioenergetics F1Fo-ATP synthase ion-to-ATP ratio photosynthesis regulation rotor c -ring Cellular life depends on the energy...

... ( p.stroh@ucl.ac.uk ) 6 11 2019 8 11 2019 8 11 2019 © 2019 The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society 2019 bioenergetics calcium complex I mitochondria reactive oxygen species Introduction Mitochondria...

... Commons Attribution License 4.0 (CC BY) . bioenergetics cardioprotection creatine kinase ischaemia–reperfusion injury The energy requirements of the human heart are exceptionally high, requiring the equivalent of 6 kg ATP (adenosine triphosphate) per day [ 1 ]. This relies...

... and distributed under the Creative Commons Attribution License 4.0 (CC BY) . bioenergetics cardiac hypertrophy metabolism mitochondrial dysfunction sodium Cardiovascular disease is the leading cause of mortality worldwide with its incidence projected to rise significantly in the immediate...

...Charles Affourtit; Ben Alberts; Jonathan Barlow; Jane E. Carré; Anthony G. Wynne The canonical model of glucose-stimulated insulin secretion (GSIS) by pancreatic β-cells predicts a glucose-induced rise in the cytosolic ATP/ADP ratio. Such bioenergetic sensitivity to metabolic fuel is unusual...

... in this subclass of enzymes. 1 To whom correspondence should be addressed (email matthias.stein@mpi-magdeburg.mpg.de ). 8 8 2013 © 2013 The Authors 2013 bioenergetics hydrogen conversion iron–sulfur cluster (Fe–S cluster) oxygen-tolerant hydrogenase protein structural modelling...

... conservation of core subunits suggests that the mechanism of complex I is conserved throughout all species, therefore we can use the bacterial enzyme as a ‘minimal’ model of human complex. Bioenergetics in Mitochondria, Bacteria and Chloroplasts: Third Joint German/UK Bioenergetics Conference...

... D.G. Brand M.D. Experimental assessment of bioenergetic differences caused by the common European mitochondrial DNA haplogroups H and T Gene 2008 411 69 76 40 Amo T. Brand M.D. Were inefficient mitochondrial haplogroups selected during migrations of modern humans? A test...

... a bioenergetic crisis by so severely limiting cellular access to extracellular nutrients that autophagy is insufficient to meet the metabolic demands of the cell. In keeping with this bioenergetic explanation for ceramide toxicity, methyl pyruvate, a membrane-permeable nutrient, protects cells from ceramide...

...]. Thus a flux-control coefficient of an enzyme within a metabolic network indicates the extent to which the pathway flux is changed in the steady state when changing the activity of this one enzyme. Control analysis of oxidative phospho- Key words: bioenergetics, isolated perfused liver, top-down...