... and temporal aspects for the control of signalling and how these concepts may influence future drug development. 1 To whom correspondence should be addressed (email denise.wootten@monash.edu ). 7 1 2016 © 2016 Authors; published by Portland Press Limited 2016 biased signalling G...

... receptor conformations that are currently not accessible through orthosteric targeting. This review addresses the emerging concepts in the development of pepducins including the elicitation of biased signalling, pepducin polypharmacology and recent insight into their mechanism of action. 1 To whom...

...@monash.edu ). 24 9 2012 © The Authors Journal compilation © 2013 Biochemical Society 2013 allosteric modulation biased signalling G-protein-coupled receptor glucagon-like peptide-1 receptor glucagon-like peptide-1 probe-dependence Type 2 DM (diabetes mellitus) is a global...