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Keywords: benzyl-O-N-acetyl-D-galactosamine
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Biochem Soc Trans (2007) 35 (5): 1372–1374.
Published: 25 October 2007
... appropriate inhibitors to identify stage-specific events. We have adopted this approach to study a group of benzyl- O - N -acetyl- D -galactosamine analogues in human colorectal cancer cell lines. Exposure to O-glycan inhibitors resulted in the induction of apoptosis, a block in proliferation, accumulation...
Biochem Soc Trans (2005) 33 (4): 721–723.
Published: 01 August 2005
... a library of O-glycosylation inhibitors based on benzyl- O - N -acetyl- D -galactosamine. These inhibitors were tested with an established series of human colorectal cancer cell lines, which model the adenoma-carcinoma sequence. Cancer cells were incubated with the inhibitors, and examined for cell growth...