... that enhances the sexual behaviour of female mice via the VNO. NMR studies demonstrate that ESP1 adopts a compact structure with a helical fold stabilized by an intramolecular disulfide bridge. Functional analysis in combination with docking simulation indicates that ESP1 is recognized by a specific G-protein...

... of the respective death routines of synapses and cell bodies. Mice with prion disease can be cured at the stage of early synaptic dysfunction, when they have reversible impairments at neurophysiological, behavioural and morphological levels. Critically, reversing synaptic dysfunction at this stage of disease...

...-arrestin-2. It is not known which of these targets is responsible for the behavioural or therapeutic effects of lithium in vivo . The present review discusses basic criteria that can be applied to model systems to validate a proposed direct target of lithium. In this context, we describe a set of simple...

... held at University of Liverpool, Liverpool, 4–6 September 2002 6 September 2002 Copyright 2003 Biochemical Society 2003 behaviour communication MUP rodent semiochemistry Abbreviations used: MHC, major histocompatibility complex; MUP, major urinary protein; uMUP...

... to lactate following their first pregnancy. Male and female homozygotes have markedly elevated serum prolactin levels, and in some instances pituitary hyperplasia is present. Maternal behaviour is severely affected in both hemizygous and homozygous animals. Bone formation is reduced in young animals...