... snRNA 5′-splice site base pairing and would not pick this up. We review these mechanisms and how an up-to-date donor splice site mutation repertoire indicates the heterogeneity of the molecular mechanism. We suggest that, in clinical molecular genetics, it is important to evaluate sequence variants...

...-strasbg.fr 27 8 2002 © 2002 Biochemical Society 2002 base pairing self-splicing tertiary structure rms, root mean square Ribozymes and RNA Catalysis: Focused Meeting Organized by D. M. J. Lilley (Department of Biochemistry, University of Dundee) and F. Eckstein (Max...