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Biochem Soc Trans (2023) 51 (1): 259–274.
Published: 06 January 2023
... that contributes to the pathogenesis of various neurological diseases. However, there is increasing evidence that reactive astrocytes also play an important role in the response to viruses. In this review article, we summarize the recent contributions of microglia and astrocytes to the neurological impairments...
Biochem Soc Trans (2021) 49 (3): 1375–1384.
Published: 07 May 2021
.... However, despite the significant amount of research done in the past decade, the contribution of LRRK2 mutations to PD pathogenesis remains unknown. Growing evidence highlights that LRRK2 controls multiple processes in brain immune cells, microglia and astrocytes, and suggests that deregulated LRRK2...
Biochem Soc Trans (2016) 44 (1): 40–45.
Published: 09 February 2016
... into energy metabolism and mitochondrial calcium handling to activation of permeability transition pore (PTP) and cell death. PolyP is a gliotransmitter which transmits the signal in astrocytes via activation of P2Y1 receptors and stimulation of phospholipase C. PolyP-induced calcium signal in astrocytes can...
Biochem Soc Trans (2000) 28 (4): 452–455.
Published: 01 August 2000
... disease and in pathologies involving oxidative stress. 1 To whom correspondence should be addressed (e-mail email@example.com ) 2 3 2000 © 2000 Biochemical Society 2000 activity-dependent neuroprotective protein activity-dependent neurotrophic factor astrocytes cell death...