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Biochem Soc Trans (2011) 39 (2): 443–445.
Published: 22 March 2011
... process regulated by amino acids, we have demonstrated recently that arginine plays a role in the activation of LPS (lipopolysaccharide)-induced MEK [MAPK (mitogen-activated protein kinase)/ERK (extracellular-signal-regulated kinase) kinase]/ERK signalling in macrophages. PP2A similarly associates...
Biochem Soc Trans (2010) 38 (5): 1322–1328.
Published: 24 September 2010
... 2010 Biochemical Society 2010 arginine half-life mathematical model mitochondrion NaH 14 CO 3 pulse–chase We are interested in mitochondrial turnover because replacing damaged mitochondria is an important potential quality control mechanism. Mitochondrial dysfunction...
Biochem Soc Trans (2007) 35 (2): 322–325.
Published: 20 March 2007
...E.W. Gerner Colon cancer in humans is influenced by both genetic and dietary risk factors. The majority of colon cancers have somatic mutations in the APC (adenomatous polyposis coli) tumour-suppressor gene. Dietary arginine enhances the risk of APC-dependent colon carcinogenesis in mouse models...