... to be linked to anxiety phenotypes, but other related discordant findings have doubted the association with glyoxalase I and further investigation is required. Glo1 CNV in mice has also been linked to increased Glo1 expression and may therefore be linked to metabolic phenotypes, such as obesity...

.... In cortical circuits, these neurons control spike timing of the principal cells, sculpt neuronal rhythms, select cell assemblies and implement brain states. On the basis of these considerations, the deficits in cognition, emotion and perception in psychiatric disorders such as anxiety, depression...