... subversion in bacterial infections. Correspondence: Pyong Woo Park ( pyong.park@childrens.harvard.edu ) 3 1 2018 19 1 2018 26 1 2018 Sdc1 ectodomains also bind to cationic antimicrobial peptides and inhibit their ability to kill bacterial pathogens in an HS-dependent manner [ 18...

... with AMPs (antimicrobial peptides), the interplay between charge and hydrophobic character of the nuclease domains governs their pleiotropic membrane activities and these results form the basis of ongoing work to unravel the molecular mechanisms underlying their membrane translocation. antimicrobial...

... (minimum inhibitory concentration) values in the single nanomolar range against sensitive targets [ 15 ]. 1 To whom correspondence should be addressed (email c.hill@ucc.ie ). 27 7 2012 © 2012 The Authors Journal 2012 antimicrobial peptide bacteriocin bioengineering...

... are antimicrobial peptides. In the present review, we provide an overview of antifungal peptides isolated from plants, insects, amphibians and mammals that induce apoptosis. Their antifungal spectrum, mode of action and toxicity are discussed in more detail. 1 To whom correspondence should be addressed...

...-regensburg.de ). 17 1 2011 © The Authors Journal compilation © 2011 Biochemical Society 2011 antimicrobial peptide bactericidal/permeability-increasing protein (BPI) cystic fibrosis lung innate immunity pneumonia From all existing data we can conclude that BPI is an important...

... in Gram-negative bacteria-induced respiratory infection. 1 email peterdi@pitt.edu 5 4 2011 © The Authors Journal compilation © 2011 Biochemical Society 2011 antimicrobial peptide bacterium lipopolysaccharide (LPS) mucous cell serous cell short palate lung and nasal...

...K. Aggrawal; N. Silverman Drosophila rely primarily on innate immune responses to effectively combat a wide array of microbial pathogens. The hallmark of the Drosophila humoral immune response is the rapid production of AMPs (antimicrobial peptides) by the fat body, the insect homologue...

... the antibacterial activity of a wide range of antimicrobial peptides and proteins: i.e. lysozyme, SLPI (secretory leucocyte proteinase inhibitor), LL-37, hNP-1 (human neutrophil peptide-1) and the human β-defensins 1, 2 and 3. Analysis of the functional properties of recombinant domains of SIC shows that binding...

...P.S. Hiemstra Innate immunity provides an effective first line of defence against infections. This is of particular importance in the lung, an organ that is exposed to a large number of pathogens that are inhaled. Antimicrobial peptides play an important role in the defence against these pathogens...

... correspondence should be addressed (email Dominic.Campopiano@ed.ac.uk ). 13 1 2006 © 2006 The Biochemical Society 2006 antimicrobial peptide defensin mass spectrometry The mammalian innate immune system produces a large array of weapons to protect the host from the constant attack...

... J.Dorin@hgu.mrc.ac.uk ). 5 1 2006 © 2006 The Biochemical Society 2006 antimicrobial peptide β-defensin gene cluster immune defence primate evolution propeptide region Antimicrobial peptides have a critical role in the vertebrate innate immune defence against microbes...