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Keywords: antimicrobial peptide
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Articles
Biochem Soc Trans (2018) 46 (2): 371–377.
Published: 09 March 2018
... subversion in bacterial infections. Correspondence: Pyong Woo Park ( pyong.park@childrens.harvard.edu ) 3 1 2018 19 1 2018 26 1 2018 © 2018 The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society 2018 antimicrobial peptide...
Articles
Biochem Soc Trans (2012) 40 (6): 1517–1521.
Published: 21 November 2012
... with AMPs (antimicrobial peptides), the interplay between charge and hydrophobic character of the nuclease domains governs their pleiotropic membrane activities and these results form the basis of ongoing work to unravel the molecular mechanisms underlying their membrane translocation. 1 To whom...
Articles
Biochem Soc Trans (2012) 40 (6): 1492–1497.
Published: 21 November 2012
... To whom correspondence should be addressed (email c.hill@ucc.ie ). 27 7 2012 © 2012 The Authors Journal 2012 antimicrobial peptide bacteriocin bioengineering lantibiotic mutagenesis nisin Perhaps the most fascinating bacteriocins are the lanthionine-containing antibiotics...
Articles
Biochem Soc Trans (2011) 39 (5): 1527–1532.
Published: 21 September 2011
... are antimicrobial peptides. In the present review, we provide an overview of antifungal peptides isolated from plants, insects, amphibians and mammals that induce apoptosis. Their antifungal spectrum, mode of action and toxicity are discussed in more detail. 1 To whom correspondence should be addressed (email...
Articles
Biochem Soc Trans (2011) 39 (4): 1045–1050.
Published: 20 July 2011
...-regensburg.de ). 17 1 2011 © The Authors Journal compilation © 2011 Biochemical Society 2011 antimicrobial peptide bactericidal/permeability-increasing protein (BPI) cystic fibrosis lung innate immunity pneumonia In contrast with most other human vital organs, the respiratory...
Articles
Biochem Soc Trans (2011) 39 (4): 1051–1055.
Published: 20 July 2011
... in Gram-negative bacteria-induced respiratory infection. 1 email peterdi@pitt.edu 5 4 2011 © The Authors Journal compilation © 2011 Biochemical Society 2011 antimicrobial peptide bacterium lipopolysaccharide (LPS) mucous cell serous cell short palate lung and nasal...
Articles
Biochem Soc Trans (2007) 35 (6): 1496–1500.
Published: 23 November 2007
...K. Aggrawal; N. Silverman Drosophila rely primarily on innate immune responses to effectively combat a wide array of microbial pathogens. The hallmark of the Drosophila humoral immune response is the rapid production of AMPs (antimicrobial peptides) by the fat body, the insect homologue...
Articles
Biochem Soc Trans (2006) 34 (2): 273–275.
Published: 20 March 2006
... the antibacterial activity of a wide range of antimicrobial peptides and proteins: i.e. lysozyme, SLPI (secretory leucocyte proteinase inhibitor), LL-37, hNP-1 (human neutrophil peptide-1) and the human β-defensins 1, 2 and 3. Analysis of the functional properties of recombinant domains of SIC shows that binding...
Articles
Biochem Soc Trans (2006) 34 (2): 276–278.
Published: 20 March 2006
...P.S. Hiemstra Innate immunity provides an effective first line of defence against infections. This is of particular importance in the lung, an organ that is exposed to a large number of pathogens that are inhaled. Antimicrobial peptides play an important role in the defence against these pathogens...
Articles
Biochem Soc Trans (2006) 34 (2): 251–256.
Published: 20 March 2006
... that the Defr1 dimer contained a novel intramolecular S–S bond, a number of other defensin-related peptides with this structural feature were reported and we discuss these below. antimicrobial peptide defensin mass spectrometry The mammalian innate immune system produces a large array...
Articles
Biochem Soc Trans (2006) 34 (2): 257–262.
Published: 20 March 2006
... The Biochemical Society 2006 antimicrobial peptide β-defensin gene cluster immune defence primate evolution propeptide region Antimicrobial peptides have a critical role in the vertebrate innate immune defence against microbes. These peptides have potential as therapeutics, and intelligent drug...