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Biochem Soc Trans (2022) 50 (5): 1315–1328.
Published: 05 October 2022
.... 14 7 2022 7 9 2022 12 9 2022 © 2022 The Author(s) 2022 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY-NC-ND) . antibiotics biosynthesis drug...
Biochem Soc Trans (2022) 50 (5): 1269–1279.
Published: 12 September 2022
...Callaghan Cylke; Fangwei Si; Shiladitya Banerjee Characterizing the physiological response of bacterial cells to antibiotic treatment is crucial for the design of antibacterial therapies and for understanding the mechanisms of antibiotic resistance. While the effects of antibiotics are commonly...
Biochem Soc Trans (2020) 48 (5): 2139–2149.
Published: 02 October 2020
... of antibiotic resistance has catalysed a renewed interest in understanding the mechanisms underlying the dynamics of antibiotics interaction with the bacterial cell envelope. It is widely recognised that the key reason behind the remarkable success of Gram-negative pathogens in developing antibiotic resistance...
Biochem Soc Trans (2020) 48 (5): 2029–2037.
Published: 11 September 2020
...J. Shaun Lott Mycobacterium tuberculosis , the causative agent of tuberculosis (TB), is the most significant cause of death from a single infectious agent worldwide. Antibiotic-resistant strains of M. tuberculosis represent a threat to effective treatment, and the long duration, toxicity...
Biochem Soc Trans (2019) 47 (1): 477–486.
Published: 19 February 2019
...Ciara Tyrrell; Catherine M. Burgess; Fiona P. Brennan; Fiona Walsh Antibiotic resistance is currently one of the greatest threats to human health. The global overuse of antibiotics in human medicine and in agriculture has resulted in the proliferation and dissemination of a multitude of antibiotic...
Biochem Soc Trans (2019) 47 (1): 339–350.
Published: 15 January 2019
...Hamed Mosaei; John Harbottle Transcription, the first phase of gene expression, is performed by the multi-subunit RNA polymerase (RNAP). Bacterial RNAP is a validated target for clinical antibiotics. Many natural and synthetic compounds are now known to target RNAP, inhibiting various stages...
Biochem Soc Trans (2018) 46 (6): 1505–1515.
Published: 31 October 2018
... © 2018 The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society 2018 antibiotics infection malaria proteoglycan Since the discussion of all glycans would go far beyond the purpose of the present work, we focus in this minireview on the O-linked GAGs...