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Keywords: anaphase-promoting complex/cyclosome (APC/C)
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Articles
Biochem Soc Trans (2010) 38 (1): 65–71.
Published: 19 January 2010
... is not in complex with Mad2. Instead, Cdc20 forms a stable complex with BubR1 and Bub3. Mad2 catalyses the binding between Cdc20 and BubR1, which presents Cdc20 to the APC/C, targeting this cofactor for destruction [ 11 – 13 ]. anaphase-promoting complex/cyclosome (APC/C) Cdh1 cell cycle regulation cell...
Articles
Biochem Soc Trans (2010) 38 (1): 1–5.
Published: 19 January 2010
... to develop artificially fused UBDs [known as TUBEs (tandem disposition of ubiquitin-binding entities)] to generate a powerful tool to purify native polyubiquitylated proteins, reaching affinities for polyubiquitin in the nanomolar range. anaphase-promoting complex/cyclosome (APC/C) cell cycle DNA...
Articles
Biochem Soc Trans (2010) 38 (1): 72–77.
Published: 19 January 2010
... substrates. 1 To whom correspondence should be addressed (email r.wolthuis@nki.nl ). 9 11 2009 © The Authors Journal compilation © 2010 Biochemical Society 2010 anaphase-promoting complex/cyclosome (APC/C) Cdc20 cyclin mitosis Nek2A spindle checkpoint Successful...
Articles
Biochem Soc Trans (2010) 38 (1): 78–82.
Published: 19 January 2010
... 2010 anaphase-promoting complex/cyclosome (APC/C) cell cycle degron mitotic switch ubiquitination ubiquitin ligase Interestingly, several APC/C Cdc20 substrates are degraded also in the presence of an active SAC. These include cyclin A [ 41 ] and Nek2A [ 42 ]. How this degradation takes...
Articles
Biochem Soc Trans (2008) 36 (3): 405–410.
Published: 21 May 2008
... 2007 18 4024 4036 26 Zhao W.M. Fang G. Anillin is a substrate of anaphase-promoting complex/cyclosome (APC/C) that controls spatial contractility of myosin during late cytokinesis J. Biol. Chem. 2005 280 33516 33524 27 Acquaviva C. Herzog F. Kraft C...