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Keywords: anaphase-promoting complex/cyclosome (APC/C)
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Articles

Searching for the boundaries: unlimited expansion of ubiquitin and ubiquitin-like signals in multiple cellular functions

Bernat Crosas, Rosa Farràs, Gemma Marfany, Manuel S. Rodríguez, Timothy M. Thomson
Journal: Biochemical Society Transactions
Biochem Soc Trans (2010) 38 (1): 1–5.
https://doi.org/10.1042/BST0380001
Published: 19 January 2010
... or timothy.thomson@ibmb.csic.es ). 13 11 2009 © The Authors Journal compilation © 2010 Biochemical Society 2010 anaphase-promoting complex/cyclosome (APC/C) cell cycle DNA-damage repair proteasome small ubiquitin-related modifier (SUMO) ubiquitin Acquisition of complexity...
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Articles

The anaphase-promoting complex/cyclosome (APC/C): cell-cycle-dependent and -independent functions

Eusebio Manchado, Manuel Eguren, Marcos Malumbres
Journal: Biochemical Society Transactions
Biochem Soc Trans (2010) 38 (1): 65–71.
https://doi.org/10.1042/BST0380065
Published: 19 January 2010
...-bisphosphatase-3), by APC/C–Cdh1 [ 38 ]. anaphase-promoting complex/cyclosome (APC/C) Cdh1 cell cycle regulation cell division cycle 20 (Cdc20) spindle assembly checkpoint (SAC) Control of neuronal function by the APC/C seems to have relevant consequences in vivo . Cdh1 heterozygous mice...
View article titled, The <span class="search-highlight">anaphase</span>-<span class="search-highlight">promoting</span> <span class="search-highlight">complex</span>&#x2F;<span class="search-highlight">cyclosome</span> (<span class="search-highlight">APC</span>&#x2F;<span class="search-highlight">C</span>): cell-cycle-dependent and -independent functions
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Articles

Cyclin A and Nek2A: APC/C–Cdc20 substrates invisible to the mitotic spindle checkpoint

Wouter van Zon, Rob M.F. Wolthuis
Journal: Biochemical Society Transactions
Biochem Soc Trans (2010) 38 (1): 72–77.
https://doi.org/10.1042/BST0380072
Published: 19 January 2010
... Biochemical Society 2010 anaphase-promoting complex/cyclosome (APC/C) Cdc20 cyclin mitosis Nek2A spindle checkpoint Successful cell division critically depends on ubiquitin-dependent destruction of mitotic regulatory proteins [ 1 , 2 ]. In mitosis, the APC/C directs the destruction...
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Articles

Fifteen years of APC/cyclosome: a short and impressive biography

Kobi J. Simpson-Lavy, Yifat S. Oren, Oren Feine, Julia Sajman, Tammy Listovsky, Michael Brandeis
Journal: Biochemical Society Transactions
Biochem Soc Trans (2010) 38 (1): 78–82.
https://doi.org/10.1042/BST0380078
Published: 19 January 2010
... determinant of APC/C-specific destruction. anaphase-promoting complex/cyclosome (APC/C) cell cycle degron mitotic switch ubiquitination ubiquitin ligase Other terminally differentiated cells such as brain neurons will never resume division, so that it is unlikely that the APC/C plays in them...
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Articles

Control of mitotic exit and cytokinesis by the APC/C

Catherine Lindon
Journal: Biochemical Society Transactions
Biochem Soc Trans (2008) 36 (3): 405–410.
https://doi.org/10.1042/BST0360405
Published: 21 May 2008
... 2007 18 4024 4036 26 Zhao W.M. Fang G. Anillin is a substrate of anaphase-promoting complex/cyclosome (APC/C) that controls spatial contractility of myosin during late cytokinesis J. Biol. Chem. 2005 280 33516 33524 27 Acquaviva C. Herzog F. Kraft C...
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