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Keywords: anaphase-promoting complex
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Articles
Biochem Soc Trans (2015) 43 (1): 19–22.
Published: 26 January 2015
... and dissolving sister-chromatid cohesion. However, it is less well-understood how this dissolution of cohesion occurs synchronously on all chromosomes at the onset of anaphase. At the centre of the action is the anaphase-promoting complex/cyclosome (APC/C), an E3 ubiquitin ligase that, in association with its...
Articles
Biochem Soc Trans (2010) 38 (6): 1639–1644.
Published: 24 November 2010
... Earnshaw (Wellcome Trust Centre for Cell Biology, Edinburgh, U.K.), Kevin Hardwick (Wellcome Trust Centre for Cell Biology, Edinburgh, U.K.) and Margarete Heck (Queen's Medical Research Institute, Edinburgh, U.K.). APC/C anaphase-promoting complex/cyclosome Cdc cell division cycle CDK...
Articles
Biochem Soc Trans (2006) 34 (4): 583–586.
Published: 21 July 2006
...K.B. Jeganathan; J.M. van Deursen Cdc20 (cell division cycle 20) and Cdh1 are the activating subunits of APC (anaphase-promoting complex), an E3-ubiquitin ligase that drives cells into anaphase by inducing degradation of cyclin B and the anaphase inhibitor securin. To prevent chromosome...