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Keywords: amyloid-β peptide
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Biochem Soc Trans (2023) 51 (1): 147–159.
Published: 11 January 2023
...Rima Budvytyte; Gintaras Valincius Misfolding, aggregation and accumulation of Amyloid-β peptides (Aβ) in neuronal tissue and extracellular matrix are hallmark features of Alzheimer's disease (AD) pathology. Soluble Aβ oligomers are involved in neuronal toxicity by interacting with the lipid...
Biochem Soc Trans (2015) 43 (5): 920–923.
Published: 09 October 2015
...) amyloid-β peptide microglia phagocytosis ABCA7 is a member of the ‘A’ subfamily of ATP-binding cassette transporters that were initially characterized by their capacity to transport lipids and other lipophilic molecules across membranes [ 9 ]. Similar to ABCA1 (the closest ABCA7 homologue...
Biochem Soc Trans (2004) 32 (1): 144–146.
Published: 01 February 2004
...A.V. Alessenko; A.E. Bugrova; L.B. Dudnik Alzheimer's disease (AD) is characterized by progressive decline in cognition, memory and intellect. It has been hypothesized that amyloid-β peptide (A-β) may have a prominent role in neurodegeneration. Oxidative mechanisms have been implicated...
Biochem Soc Trans (2002) 30 (4): 525–529.
Published: 01 August 2002
...B. Wolozin Accumulation of a 40–42-amino acid peptide, termed amyloid-β peptide (Aβ), is associated with Alzheimer's disease (AD), and identifying medicines that inhibit Aβ could help patients with AD. Recent evidence suggests that a class of medicines that lower cholesterol by blocking the enzyme...
Biochem Soc Trans (2002) 30 (4): 530–534.
Published: 01 August 2002
..., Oklahoma Medical Research Foundation (e-mail Jordan-tang@omrf.ouhsc.edu ) 15 3 2002 © 2002 Biochemical Society 2002 Alzheimer's disease amyloid-β peptide β-amyloid precursor protein inhibitor drug APP, amyloid-β precursor protein Aβ, amyloid-β peptide AD, Alzheimer's disease...
Biochem Soc Trans (2002) 30 (4): 534–537.
Published: 01 August 2002
...D. Beher; M. S. Shearman Development of Alzheimer's disease (AD) pathology appears to be causally related to age-dependent changes in the metabolism of the amyloid-β peptide (Aβ), leading to its enhanced aggregation and deposition.γ-Secretase is a crucial enzyme for the generation of Aβ from...
Biochem Soc Trans (2001) 29 (4): 601–606.
Published: 01 August 2001
... © 2001 Biochemical Society 2001 amyloid-β peptide α-helix → β-strand transition prion protein protein structure secondary structure prediction Aβ, amyloid-β ES, electrospray PAP, pulmonary alveolar proteinosis PrP, prion protein SP-C, surfactant protein C DPPC...