..., such as vesicle fusion and trafficking, specialized membrane organization and actin organization [ 57 , 58 ]. Alzheimer's disease amyloid β-peptide complement system disease modelling genome-wide association study (GWAS) lipid metabolism The recent advances in AD (Alzheimer's disease) genetics...

... accumulation of Aβ (amyloid β-peptide), a central event in AD (Alzheimer's disease) synaptic dysfunctions. Structural alterations introduced by site-specific modifications linked to protein aging may affect Aβ production, polymerization and clearance, and therefore play a pivotal role in the pathogenesis...

... of Aβ. The production of Aβ (amyloid β-peptide) and its aggregation into SPs (senile plaques) is thought to be responsible for the cognitive decline observed in patients with AD (Alzheimer's disease) [ 1 ]. Epidemiological studies have shown that patients on long-term statin treatment...