... -acting regulators of alternative cleavage and polyadenylation. FCA and FPA directly associate with chromatin at the locus encoding the floral repressor FLC, but appear to control FLC transcription by mediating alternative polyadenylation of embedded non-coding antisense RNAs. These findings prompt the re...

... reveal that an integral part of ELAV gene-specific regulation involves combinatorial binding to variably spaced short U-rich motifs on an extensive binding site. alternative polyadenylation alternative splicing embryonic lethal abnormal visual system (ELAV) nervous system development RNA...

... , and in Drosophila erecta . The A/Q N-terminal domain is specific to the Drosophila lineage and is not involved in RNA binding ( Figure 2 ) [ 11 ]. alternative polyadenylation alternative splicing embryonic lethal abnormal visual system (ELAV) erect wing gene ( ewg gene) evolution nervous system...

... The Authors Journal compilation © 2008 Biochemical Society 2008 Affymetrix GeneChip alternative polyadenylation alternative splicing microarray post-transcriptional processing RNA Microarrays are pervasive technology, widely used in the life sciences to measure genome-wide transcriptional...

...) regulation of COX-2 involves alternative polyadenylation. 1 To whom correspondence should be addressed (email A.J.Tyson-Capper@ncl.ac.uk ). 6 2 2008 © The Authors Journal compilation © 2008 Biochemical Society 2008 alternative polyadenylation cyclo-oxygenase-2 (COX-2) mRNA...

..., with transcripts arising as the result of alternative splicing and alternative polyadenylation [ 4 ]. FCA intron 3 is a particularly important site of regulation, as transcripts can be detected in which this intron is retained (transcript α) or excised (transcript γ) or in which premature cleavage...