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Keywords: allosteric regulation
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Articles
Biochem Soc Trans (2022) BST20220547.
Published: 18 November 2022
.... 17 8 2022 9 10 2022 12 10 2022 Correspondence: Dmitry Lyumkis ( dlyumkis@salk.edu ) or Nancy C. Horton ( nhorton@email.arizona.edu ) CTPS cytosine triphosphate synthase IM-MS ion mobility native mass RM restriction-modification allosteric regulation DNA...
Articles
Biochem Soc Trans (2022) 50 (1): 71–82.
Published: 22 February 2022
... © 2022 The Author(s) 2022 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY-NC-ND) . allosteric regulation retinitis pigmentosa splice variants Inosine...
Articles
Biochem Soc Trans (2021) 49 (2): 591–607.
Published: 26 March 2021
...Chen Davidovich; Qi Zhang Histone lysine methyltransferases (HKMTs) are key regulators of many cellular processes. By definition, HKMTs catalyse the methylation of lysine residues in histone proteins. The enzymatic activities of HKMTs are under precise control, with their allosteric regulation...
Articles
Biochem Soc Trans (2021) 49 (1): 415–429.
Published: 05 February 2021
... 2021 15 1 2021 © 2021 The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society 2021 allosteric regulation computational biochemistry molecular dynamics Aromatic amino acids phenylalanine (Phe), tyrosine (Tyr), and tryptophan (Trp) are important...
Articles
Biochem Soc Trans (2019) 47 (4): 1013–1027.
Published: 11 July 2019
.... In addition, allosteric regulation further fine-tunes the catalytic activity of SAMHD1, with a nucleotide-activated homotetramer as the catalytically active form of the protein. In cells, GTP and dATP are the likely physiological activators of two adjacent allosteric sites, AL1 (GTP) and AL2 (dATP...
Articles
Biochem Soc Trans (2019) 47 (2): 733–741.
Published: 18 April 2019
... 2019 2 4 2019 © 2019 The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society 2019 Correspondence: John W Scott ( jscott@svi.edu.au ) Figure 1. Allosteric regulation of AMPK. Stress-induced increases in cellular levels of AMP and ADP trigger...
Articles
Biochem Soc Trans (2019) 47 (1): 381–388.
Published: 01 February 2019
... Society 2019 allosteric regulation cellulose synthase cyclic di-GMP flagella PilZ domain protein–protein interactions C-di-GMP is a second messenger found in many environmental and pathogenic bacteria. C-di-GMP regulates a plethora of cellular functions and has attracted great attention...
Articles
Biochem Soc Trans (2018) 46 (3): 587–597.
Published: 20 April 2018
... on behalf of the Biochemical Society 2018 allosteric regulation fractals protein conformation protein dynamics Figure 4. Entropy/dynamics-driven allostery model. Communities of residues that move coherently as semi-rigid bodies are coded with different colors. Intermediate residues...
Articles
Biochem Soc Trans (2017) 45 (5): 1087–1095.
Published: 25 August 2017
..., and further that the ligand-binding site at the entrance of the K-path represents a physiologically important regulatory domain. 3 6 2017 14 7 2017 18 7 2017 © 2017 The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society 2017 allosteric...
Articles
Biochem Soc Trans (2017) 45 (3): 665–681.
Published: 15 June 2017
...-catalytic functions that can be exerted by conventional protein kinases. Correspondence: James Murphy ( jamesm@wehi.edu.au ) 27 1 2017 8 3 2017 9 3 2017 © 2017 The Author(s); published by Portland Press Limited on behalf of the Biochemical Society 2017 allosteric regulation...
Articles
Biochem Soc Trans (2017) 45 (3): 831–837.
Published: 15 June 2017
... of the Biochemical Society 2017 allosteric regulation azobenzene molecular machine photoswitch protein engineering Re-engineering of biological materials to control cellular and molecular functions via external stimuli is of great interest in the field of Synthetic Biology and might have useful...
Articles
Biochem Soc Trans (2014) 42 (1): 108–113.
Published: 23 January 2014
... of the Creative Commons Attribution Licence (CC-BY) ( http://creativecommons.org/licenses/by/3.0/ ) which permits unrestricted use, distribution and reproduction in any medium, provided the original work is properly cited. allosteric regulation cGMP guanylate cyclase hypertension nitric oxide...
Articles
Biochem Soc Trans (2013) 41 (1): 205–212.
Published: 29 January 2013
...: Center for Biomembrane Research, Department of Biochemistry and Biophysics, Stockholm University, SE-10691, Stockholm, Sweden. 30 10 2012 © The Authors Journal compilation © 2013 Biochemical Society 2013 allosteric regulation conformational change GPCR (G-protein-coupled receptor...
Articles
Biochem Soc Trans (2011) 39 (2): 472–476.
Published: 22 March 2011
... structures provide fertile ground for allosteric regulation [ 37 ]. Exploiting the potential of this pocket to manipulate kinase conformation, and not just to block activity, is consequently of critical importance as we move forward in the targeting of kinases in disease. mTOR Signalling in Health...
Articles
Biochem Soc Trans (2000) 28 (2): 186–190.
Published: 01 February 2000
...,6BP, fructose 1,6-bisphosphate allosteric regulation drug design effector site fructose 2,6-bisphosphate trypanosomatid Biochemical Society Transactions (2000) Volume 28, part 2 acyl-CoA. The enzyme properties and locations are consistent with this. Above all, the carnitine derivatives...