1-6 of 6
Keywords: agonist
Close
Follow your search
Access your saved searches in your account

Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Articles
Biochem Soc Trans (2013) 41 (1): 159–165.
Published: 29 January 2013
...Tony Warne; Christopher G. Tate Structures of the inactive state of the thermostabilized β 1 -adrenoceptor have been determined bound to eight different ligands, including full agonists, partial agonists, inverse agonists and biased agonists. Comparison of the structures shows distinct differences...
Articles
Biochem Soc Trans (2009) 37 (6): 1347–1354.
Published: 19 November 2009
...-expressed with GluN1 (glycine-binding) subunits, which form the final tetrameric NMDAR assembly. Of the four GluN2 subunits that exist (termed A–D), NMDARs composed of GluN1/GluN2A and GluN1/GluN2D subunits display the greatest differences in their sensitivities to a variety of agonists, antagonists...
Articles
Biochem Soc Trans (2007) 35 (6): 1453–1455.
Published: 23 November 2007
... endemic exogenous agonists are mediated by non-BMDC (bone-marrow-derived cells), which can include endothelial cells. In contrast, the proatherogenic TLR2 responses to the defined synthetic exogenous agonist Pam3 CSK4 are mediated at least in part by BMDC, which can include lymphocytes, monocytes...
Articles
Biochem Soc Trans (2007) 35 (6): 1461–1467.
Published: 23 November 2007
... carried out extensive structure–activity relationship studies of DNA- and RNA-based compounds to elucidate the impact of nucleotide motifs and structures on these TLR-mediated immune responses. These studies have led us to design novel DNA- and RNA-based compounds, which act as potent agonists of TLR9...
Articles
Biochem Soc Trans (2007) 35 (4): 717–720.
Published: 20 July 2007
... that these extracellular domains fulfil a range of important roles with respect to GPCR signalling, including agonist binding, ligand selectivity and receptor activation. AVP [Arg 8 ]vasopressin bRho bovine rhodopsin ECL extracellular loop GPCR G-protein-coupled receptor OT oxytocin OTR...
Articles
Biochem Soc Trans (2004) 32 (6): 1048–1050.
Published: 26 October 2004
... fulfil a range of important roles with respect to GPCR signalling, including agonist binding, ligand selectivity and receptor activation. 23 7 2004 © 2004 The Biochemical Society 2004 1 To whom correspondence should be addressed (email m.wheatley@bham.ac.uk ). The role of ECL3...