...Kirsty E. Waddington; Elizabeth C. Jury; Inés Pineda-Torra The liver X receptors (LXRs), LXRα and LXRβ, are transcription factors with well-established roles in the regulation of lipid metabolism and cholesterol homeostasis. In addition, LXRs influence innate and adaptive immunity, including...

... adaptive immunity animal model gastrointestinal tract inflammatory bowel disease (IBD) innate immunity microflora pathogenicity The IBDs (inflammatory bowel diseases) are mainly represented by UC (ulcerative colitis) and Crohn's disease, but also have peripheral interactions with other...

...T. Lawrence; M. Bebien Inflammation is a beneficial response to insult or injury which plays an important role in orchestrating the adaptive immune response. The resolution of acute inflammation is an active process that involves the release of anti-inflammatory mediators and the termination of pro...