...Florian Fäßler; Manjunath G. Javoor; Florian KM Schur The actin cytoskeleton plays a key role in cell migration and cellular morphodynamics in most eukaryotes. The ability of the actin cytoskeleton to assemble and disassemble in a spatiotemporally controlled manner allows it to form higher-order...

...) and does not contain any clear homology or recognized sequence motifs. actin cytoskeleton phosphatidylinositol phosphate Sh3yl1 Src homology-3 (SH3) domain SYLF domain Ysc84 actin-binding (YAB) domain Ysc84 The actin filament network plays a central role in many cellular processes from...

... GTPases from yeast to humans is to control the actin cytoskeleton, although, in addition, they promote a wide range of other cellular activities. Changes in the actin cytoskeleton drive many dynamic aspects of cell behaviour, including morphogenesis, migration, phagocytosis and cytokinesis...

... in different cellular contexts. This has led to their definition in the control of various cell functions, such as cell proliferation in the thyroid and actin cytoskeleton organization in fibroblasts and lymphocytes. Roles for the glycerophosphoinositols in immune and inflammatory responses are also being...

...D.R. Critchley The cytoskeletal protein talin plays a key role in coupling the integrin family of cell adhesion molecules to the actin cytoskeleton. In this paper I present a brief review on talin and summarize our recent studies, in which we have taken both genetic and structural approaches...

...M.C. Parrini; M. Matsuda; J. de Gunzburg Pak1 (p21-activated kinase 1) is a key regulator of the actin cytoskeleton, adhesion and cell motility. Such biological roles require a tight spatial and kinetic control of its localization and activity. We summarize here the current knowledge on Pak1...

... for this localization. It is conceivable, therefore, that p122 is involved in the reorganization of the actin cytoskeleton and focal adhesions that regulate cell–substratum adhesion and cell migration. 1 To whom correspondence should be addressed (email yagisawa@sci.u-hyogo.ac.jp ). EGFP enhanced green...

... fluorescent protein; PAK1, p21-activated kinase-1; PKC, protein kinase C; RFP, red fluorescent protein. actin cytoskeleton cell migration fluorescence lifetime imaging microscopy (FLIM) fluorescence resonance energy transfer (FRET) signalling © 2004 Biochemical Society 2004 3...

... actin cytoskeleton cyclic compression gelatin zymography mechanotransduction quantitative PCR MMP, matrix metalloproteinase GAPDH, glyceraldehyde-3-phosphate dehydrogenase Connective Tissue Research Colloquium Organized and Edited by V. Duance (School of Biosciences, Cardiff University...