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Journal: Biochemical Society Transactions
Biochem Soc Trans (2013) 41 (6): 1766–1771.
Published: 20 November 2013
...Iain M. Hagan; Agnes Grallert The activation of the Cdk1 (cyclin-dependent kinase 1)–cyclin B complex to promote commitment to mitosis is controlled by the phosphorylation status of the Cdk1 catalytic subunit. Cdk1 phosphorylation by Wee1 kinases blocks activation until Cdc25 (cell division cycle...