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Keywords: Type I
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Articles
Biochem Soc Trans (2020) 48 (1): 15–23.
Published: 10 January 2020
... of the most widespread and diverse Type I systems afford tremendous opportunities for a broad range of applications. These highly abundant systems rely on a multi-protein effector complex, the CRISPR associated complex for antiviral defense (Cascade), which drives DNA targeting and cleavage. The complexity...