1-3 of 3
Keywords: Type 1 diabetes
Close
Save search
Follow your search
Access your saved searches in your account
Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Articles

Host gene effects on gut microbiota in type 1 diabetes

Keyu Guo, Juan Huang, Zhiguang Zhou
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (3): 1133–1142.
DOI: https://doi.org/10.1042/BST20220004
Published: 06 May 2022
...Keyu Guo; Juan Huang; Zhiguang Zhou Type 1 diabetes (T1D) is an organ-specific autoimmune disease characterized by progressive pancreatic β-cell loss. Both a predisposing genetic background, that may encompass mutations in several genes, as well as exposure to environmental factors can affect...
View article titled, Host gene effects on gut microbiota in <span class="search-highlight">type</span> <span class="search-highlight">1</span> <span class="search-highlight">diabetes</span>
Click here to open pdf in another window PDF for Host gene effects on gut microbiota in <span class="search-highlight">type</span> <span class="search-highlight">1</span> <span class="search-highlight">diabetes</span>
Articles

Commonality in the genetic control of Type 1 diabetes in humans and NOD mice: variants of genes in the IL-2 pathway are associated with autoimmune diabetes in both species

Dan B. Rainbow, Laura Esposito, Sarah K. Howlett, Kara M. Hunter, John A. Todd, Laurence B. Peterson, Linda S. Wicker
Journal: Biochemical Society Transactions
Biochem Soc Trans (2008) 36 (3): 312–315.
DOI: https://doi.org/10.1042/BST0360312
Published: 21 May 2008
...Dan B. Rainbow; Laura Esposito; Sarah K. Howlett; Kara M. Hunter; John A. Todd; Laurence B. Peterson; Linda S. Wicker Variants within the IL-2 (interleukin 2) and CD25 genes are associated with T1DM (Type 1 diabetes mellitus) in mice and humans respectively. Both gene products are essential...
View article titled, Commonality in the genetic control of <span class="search-highlight">Type</span> <span class="search-highlight">1</span> <span class="search-highlight">diabetes</span> in humans and NOD mice: variants of genes in the IL-2 pathway are associated with autoimmune diabetes in both species
Click here to open pdf in another window PDF for Commonality in the genetic control of <span class="search-highlight">Type</span> <span class="search-highlight">1</span> <span class="search-highlight">diabetes</span> in humans and NOD mice: variants of genes in the IL-2 pathway are associated with autoimmune diabetes in both species
Articles

Role of NF-κB in β-cell death

Danielle Melloul
Journal: Biochemical Society Transactions
Biochem Soc Trans (2008) 36 (3): 334–339.
DOI: https://doi.org/10.1042/BST0360334
Published: 21 May 2008
...Danielle Melloul Apoptotic β-cell death appears to be central to the pathogenesis of Type 1 diabetes mellitus and in islet graft rejection. The β-cell destruction is partially mediated by cytokines, such as IL-1β (interleukin 1β), TNFα (tumour necrosis factor α) and IFN-γ (interferon γ). IL-1β...
View article titled, Role of NF-κB in β-cell death
Click here to open pdf in another window PDF for Role of NF-κB in β-cell death