1-17 of 17
Keywords: Toll-like receptor (TLR)
Close
Follow your search
Access your saved searches in your account

Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Articles
Biochem Soc Trans (2014) 42 (1): 11–24.
Published: 23 January 2014
... (PI3K) salt-inducible kinase (SIK) Toll-like receptor (TLR) In contrast with the production of pro-inflammatory cytokines, the Tpl2/MKK1/ERK1/2 cascade limits the production of Type I IFNs in macrophages. Genetic deletion of Tpl2 or pharmacological inhibition of MKK1 prevents ERK1/2 activation...
Articles
Biochem Soc Trans (2012) 40 (5): 1134–1139.
Published: 19 September 2012
... is sufficient for interaction with microtubules J. Neurosci. Res. 2008 86 1711 1720 © The Authors Journal compilation © 2012 Biochemical Society 2012 cytokine immune system leucine-rich repeat kinase 2 (LRRK2) Parkinson's disease receptor-interacting protein kinase (RIPK) Toll-like...
Articles
Biochem Soc Trans (2011) 39 (5): 1233–1239.
Published: 21 September 2011
... c.m.spickett@aston.ac.uk ). 24 5 2011 © The Authors Journal compilation © 2011 Biochemical Society 2011 chlorinated phospholipid inflammation mass spectrometry oxidized phospholipid (oxPL) precursor ion scanning Toll-like receptor (TLR) The interest in lipids as mediators...
Articles
Biochem Soc Trans (2009) 37 (4): 863–867.
Published: 22 July 2009
... pbuchanan03@qub.ac.uk ). 4 3 2009 © The Authors Journal compilation © 2009 Biochemical Society 2009 cystic fibrosis inflammation lipid A lipopolysaccharide Pseudomonas aeruginosa Toll-like receptor (TLR) CF (cystic fibrosis; OMIM no. 219700) is a lethal autosomal recessive...
Articles
Biochem Soc Trans (2008) 36 (6): 1448–1451.
Published: 19 November 2008
... (SOCS) Toll-like receptor (TLR) Cytokines are small messenger molecules that are involved in cell–cell communication and are critical to many vital processes such as embryonic development, growth, haemopoiesis and immune responses. They cannot cross the cellular membrane but make use...
Articles
Biochem Soc Trans (2007) 35 (6): 1453–1455.
Published: 23 November 2007
... Biochemical Society 2007 agonist atherosclerosis cholesterol endothelial cell macrophage Toll-like receptor (TLR) Initial results with double knockout LDLr −/− TLR2 −/− mice showed that whole body deficiency of TLR2 results in decreased lesion burden after 10 or 14 weeks of consuming a high...
Articles
Biochem Soc Trans (2007) 35 (6): 1512–1514.
Published: 23 November 2007
... 2007 © The Authors Journal compilation © 2007 Biochemical Society 2007 antiviral signalling pattern-recognition receptor retinoic-acid-inducible protein I (RIG-I) Toll-like receptor (TLR) vaccinia virus viral immune evasion The initially described ligands for TLRs were mainly...
Articles
Biochem Soc Trans (2007) 35 (6): 1515–1518.
Published: 23 November 2007
... Dynamics myeloid differentiation factor 88 (MyD88) Toll-like receptor (TLR) We thank Claus-Wilhelm von der Lieth and Thomas Holz for advice on homology modelling and computer support. A.N.R.W. and A.K. were funded by the Deutsche Forschungsgemeinschaft Emmy Noether Programme and DKFZ (Deutsches...
Includes: Supplementary data
Articles
Biochem Soc Trans (2007) 35 (6): 1456–1460.
Published: 23 November 2007
... papillomavirus (HPV) interferon (IFN) Toll-like receptor (TLR) CIN cervical intra-epithelial neoplasia DC dendritic cell HPV human papillomavirus IFN interferon IRF IFN regulatory factor ISRE IFN-specific response element LC Langerhans cell ORF open reading...
Articles
Biochem Soc Trans (2007) 35 (6): 1449–1452.
Published: 23 November 2007
... (email j.a.mitchell@imperial.ac.uk ). 29 8 2007 © The Authors Journal compilation © 2007 Biochemical Society 2007 blood vessel cardiac myocyte endothelium nucleotide oligomerization domain (NOD) pattern-recognition receptor Toll-like receptor (TLR) Blood vessels...
Articles
Biochem Soc Trans (2007) 35 (6): 1437–1444.
Published: 23 November 2007
...) Toll-like receptor (TLR) The recent and ongoing identification of germline-encoded innate immune PRRs (pattern-recognition receptors), as a first line of host defence, has revolutionized our understanding of innate immunity [ 1 , 2 ]. These receptors are central to the innate immune system...
Articles
Articles
Biochem Soc Trans (2007) 35 (6): 1473–1478.
Published: 23 November 2007
... pathways) and TAK-1 [TGF-β (transforming growth factor β)-activated kinase] [ 7 ]. cancer colitis Crohn's disease inflammatory bowel disease (IBD) intestine Toll-like receptor (TLR) COX-2 expression is elevated in the inflamed mucosa of IBD as well as in CAC lesions in IBD patients [ 80...
Articles
Biochem Soc Trans (2006) 34 (5): 957–959.
Published: 25 October 2006
...-mobility group box 1 (HMGB1) ischaemia/reperfusion injury nitric oxide synthase Toll-like receptor (TLR) Depending on the enzymatic source {eNOS [endothelial NOS (NO synthase)] compared with iNOS (inducible NOS)} and the type of I/R (cold compared with warm), NO can play either a protective...
Articles
Biochem Soc Trans (2006) 34 (6): 1352–1355.
Published: 25 October 2006
... ischaemic injury lipopolysaccharide (LPS) neuroprotection tolerance Toll-like receptor (TLR) tumour necrosis factor (TNF) Hsp heat-shock protein IFN interferon IRF IFN regulatory factor LPS lipopolysaccharide NF-κB nuclear factor κB ODN oligodeoxynucleotide...
Articles
Biochem Soc Trans (2003) 31 (3): 659–663.
Published: 01 June 2003
..., a Biochemical Society Focused Meeting held at Novartis, Horsham, 3 February 2003 7 March 2003 © 2003 Biochemical Society 2003 Drosophila Toll-like receptor (TLR) dToll Abbreviations used: dToll, Drosophila Toll; LRR, leucine-rich repeat; IL(−1R), interleukin(−1 receptor...
Articles
Biochem Soc Trans (2003) 31 (3): 637–642.
Published: 01 June 2003
...S. Akira; M. Yamamoto; K. Takeda Toll-like receptors (TLRs) play a critical role in the detection of invading pathogens within the body and the subsequent immune response. Individual TLRs recognize distinct microbial components. The TLRs are a type 1 transmembrane receptor that possess...