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Stress granules: sites of mRNA triage that regulate mRNA stability and translatability

N. Kedersha, P. Anderson

Biochem Soc Trans (2002) 30 (6): 963–969.

https://doi.org/10.1042/bst0300963

Published: 01 November 2002

...; SG, stress granule; TIA- I, T-cell internal antigen- I ; TIAR. TIA- I related protein; TNF, tumour necrosis factor; TTP, tristetraprolin. 'To whom correspondence should be addressed (e-rnail nkedersha@rics.bwh.harvard.edu). 963 Abstract Mammalian stress granules (SGs) are cytoplasmic domains...

View article titled, Stress granules: sites of mRNA triage that regulate mRNA stability and translatability

Articles

Tristetraprolin and other CCCH tandem zinc-finger proteins in the regulation of mRNA turnover

P. J. Blackshear

Biochem Soc Trans (2002) 30 (6): 945–952.

https://doi.org/10.1042/bst0300945

Published: 01 November 2002

..., granulocyte/macrophage colony-stimulating factor GOS24, G0/G1 switch regulatory gene 24 KO, knockout LPS, lipopolysaccharide MAP, mitogen-activated protein NUP475, nuclear protein 475 poly(A)+, polyadenylated TISII, TPA-induced sequence II TNF, tumour necrosis factor TTP, tristetraprolin WT, wild...

View article titled, Tristetraprolin and other CCCH tandem zinc-finger proteins in the regulation of mRNA turnover

Articles

AU-rich element-mediated translational control: complexity and multiple activities of trans -activating factors

T. Zhang, V. Kruys, G. Huez, C. Gueydan

Biochem Soc Trans (2002) 30 (6): 952–958.

https://doi.org/10.1042/bst0300952

Published: 01 November 2002

...-2; poly(A polyadenylated ; RRM, RNA recognition motif; TIA- I , T-cell intracellular antigen- I ; TIAR, TIA- I -related protein; TNF, tumour necrosis factor; TTP, tristetraprolin. To whom correspondence should be addressed (e-mail cgueydan @ulb.ac.be). T T P binding to the T N F - a ARE, indicating...

View article titled, AU-rich element-mediated translational control: complexity and multiple activities of trans -activating factors

Articles

Is MK2 (mitogen-activated protein kinase-activated protein kinase 2) the key for understanding post-transcriptional regulation of gene expression?

A. Kotlyarov, M. Gaestel

Biochem Soc Trans (2002) 30 (6): 959–963.

https://doi.org/10.1042/bst0300959

Published: 01 November 2002

View article titled, Is MK2 (mitogen-activated protein kinase-activated protein kinase 2) the key for understanding post-transcriptional regulation of gene expression?

Articles

Antimicrobial activity of antiproteinases

J.-M. Sallenave

Biochem Soc Trans (2002) 30 (2): 111–115.

https://doi.org/10.1042/bst0300111

Published: 01 April 2002

... response IL-I (etc.), interleukin-1 (etc.) LPS, lipopolysaccharide SKALP, skin-derived antileucoproteinase SLPI, secretory leucocyte proteinase inhibitor TNF, tumour necrosis factor adenovirus elafin/elastase-specific inhibitor/SKALP elastase inflammation SLPI Proteases and Anti-proteases...

View article titled, Antimicrobial activity of antiproteinases

Articles

DNA damage signalling and NF-κB: implications for survival and death in mammalian cells

M. P. Boland

Biochem Soc Trans (2001) 29 (6): 674–678.

https://doi.org/10.1042/bst0290674

Published: 01 November 2001

... ataxia and Rad-related; DNA-PK. DNA-dependent protein kinase: Ku80. 80 kDa subunit of the DNA-PK holoenzyme; MTX. mitoxantrone: NF-KB. nuclear factor KB: STAT, signal transducer and activator of transcription; TNF. tumour necrosis factor: top0 II. topoisomerase II. 'e-mail mpb28(a,cam.ac.uk Transcription...

View article titled, DNA damage signalling and NF-κB: implications for survival and death in mammalian cells

Articles

Sepsis begins at the interface of pathogen and host

B. Beutler

Biochem Soc Trans (2001) 29 (6): 853–859.

https://doi.org/10.1042/bst0290853

Published: 01 November 2001

.... 1 e-mail bruce@scripps.edu 13 7 2001 © 2001 Biochemical Society 2001 endotoxin infection innate immunity lipopoly-saccharide macrophage Toll-like receptors IL, interleukin LPS, lipopolysaccharide TLR, Toll-like receptor TNF, tumour necrosis factor Signal...

View article titled, Sepsis begins at the interface of pathogen and host

Articles

Toll-like receptors: lessons from knockout mice

S. Akira

Biochem Soc Trans (2000) 28 (5): 551–556.

https://doi.org/10.1042/bst0280551

Published: 01 October 2000

..., Toll-like receptor: IL, interleukin: IL- I R, intedeukin- I receptor: IRAK, IL- I R-associated kinase; I8W, 18- wheeler: LPS, lipopolysaccharide: LBP, LPS-binding protein; NF- KB, nuclear factor KB; IKB, inhibitory K B : TNF, tumour necrosis factor; MAP kinase. mitogen-activated protein kinase. 'e...

View article titled, Toll-like receptors: lessons from knockout mice

Articles

Apoptosis and the regulation of neutrophil lifespan

Moira Whyte, Stephen Renshaw, Roderick Lawson, Colin Bingle

Biochem Soc Trans (1999) 27 (6): 802–807.

https://doi.org/10.1042/bst0270802

Published: 01 December 1999

...Moira Whyte; Stephen Renshaw; Roderick Lawson; Colin Bingle 22 7 1999 © 1999 Biochemical Society 1999 GM-CSF, granulocyte/macrophage colony-stimulating factor LPS, lipopolysaccharide TNF, tumour necrosis factor Biochemical Society Transactions ( 1999) Volume 27, part 6 19 20...

View article titled, Apoptosis and the regulation of neutrophil lifespan

Articles

Epstein-Barr virus and apoptosis: viral mimicry of cellular pathways

Lawrence S. Young, Chris W. Dawson, Aristides G. Eliopoulos

Biochem Soc Trans (1999) 27 (6): 807–812.

https://doi.org/10.1042/bst0270807

Published: 01 December 1999

...-Barr nuclear antigen EBV, Epstein-Barr virus IL, interleukin LCL, lymphoblastoid cell line LMP, latent membrane protein NPC, nasopharyngeal carcinoma TNF, tumour necrosis factor TRADD, TNF-receptor-associated death domain protein TRAF, TNF-receptor-associated factor Molecular Control...

View article titled, Epstein-Barr virus and apoptosis: viral mimicry of cellular pathways

Articles

MHC linked genes associated with apoptosis/programmed cell death

Tina Rich, Richard Stephens, John Trowsdale

Biochem Soc Trans (1999) 27 (6): 781–785.

https://doi.org/10.1042/bst0270781

Published: 01 December 1999

...Tina Rich; Richard Stephens; John Trowsdale 18 6 1999 © 1999 Biochemical Society 1999 BH3 domain, Bcl-2 homology 3 domain HSP, heat shock protein IDDM, insulin-dependent diabetes mellitus TNF, tumour necrosis factor n 0 Molecular Control of Apoptosis Host Colloquium...

View article titled, MHC linked genes associated with apoptosis/programmed cell death

Articles

Death receptors, NF- κ B activation and apoptosis: the potential for therapeutic intervention

Stuart N. Farrow

Biochem Soc Trans (1999) 27 (6): 812–814.

https://doi.org/10.1042/bst0270812

Published: 01 December 1999

...Stuart N. Farrow 18 6 1999 © 1999 Biochemical Society 1999 FLIP, FLICE-inhibitory proteins TNF, tumour necrosis factor TNFR, TNF receptor Biochemical Society Transactions ( 1999) Volume 27, part 6 48 49 Caldwell, R G., Wilson, J. B., Anderson, S. J. and Longnecker, R (I 998...

View article titled, Death receptors, NF- κ B activation and apoptosis: the potential for therapeutic intervention

Articles

Immunotherapy of auto-immune diseases by gene transfer

Yuti Chernajovsky, David Gould, Alexander Annenkov, Hanna Dreja, Gordon Daly, Gabriel A. Rabinovich, Ludovic Croxford, David Baker, Mariana Berenstein, Osvaldo Podhajcer

Biochem Soc Trans (1999) 27 (6): 869–873.

https://doi.org/10.1042/bst0270869

Published: 01 December 1999

... arthritis TNF, tumour necrosis factor IFN, interferon Th, T helper IL, interleukin TGFβ, transforming growth factor β CIA, collagen-induced arthritis EAE, experimental allergic encephalomyelitis CNS, central nervous system LTR, long terminal repeat CMV, cytomegalovirus dTNF-R, dimeric TNF...

View article titled, Immunotherapy of auto-immune diseases by gene transfer

Articles

Identification of intracellular ceramide target proteins by affinity chromatography and TID-ceramide photoaffinity labelling

M. Wickel, M. Heinrich, T. Weber, J. Brunner, M. Krönke, S. Schütze

Biochem Soc Trans (1999) 27 (4): 393–399.

https://doi.org/10.1042/bst0270393

Published: 01 August 1999

... CAPK, ceramide-activated protein kinase CBP97, 97 kDa ceramide-binding protein CPP32, caspase 3 CTSD, cathepsin D MBP, myelin basic protein TID, 3-trifluoromethyl-3-( m -iodophenyl)diazirine SMase, sphingomyelinase THF, tetrahydrofuran TNF, tumour necrosis factor TR55 p55 TNF receptor...

View article titled, Identification of intracellular ceramide target proteins by affinity chromatography and TID-ceramide photoaffinity labelling

Articles

Ceramide and apoptosis

D. K. Perry

Biochem Soc Trans (1999) 27 (4): 399–404.

https://doi.org/10.1042/bst0270399

Published: 01 August 1999

...D. K. Perry 17 4 1999 © 1999 Biochemical Society 1999 CAP kinase, ceramide-activated protein kinase PP, protein phosphatase TNF, tumour necrosis factor Sphingolipids 23 24 25 26 27 28 29 30 31 32 33 34 van der Bend, R, Brunner, J., Jalink K., van Corven, E. J., Moolenaar, H...

View article titled, Ceramide and apoptosis

Articles

The expanding superfamily of serpins: searching for the real targets

D. M. Worrall, O. E. Blacque, R. C. Barnes

Biochem Soc Trans (1999) 27 (4): 746–750.

https://doi.org/10.1042/bst0270746

Published: 01 August 1999

..., plasminogen activator inhibitor-2: PI-6, protease inhibitor-6; SCCA, squamouscell carcinomaantigen; TNF, tumour necrosis factor. 0 1999 Biochemical Society finding a physiological target. This problem was demonstrated early in serpin research in the case of al-antitrypsin, which was thus named by its ability...

View article titled, The expanding superfamily of serpins: searching for the real targets

Articles

Characterization of the tumour necrosis factor α-converting enzyme, TACE/ADAM17

D. P. Cerretti

Biochem Soc Trans (1999) 27 (2): 219–223.

https://doi.org/10.1042/bst0270219

Published: 01 February 1999

...D. P. Cerretti © 1999 Biochemical Society 1999 TACE, TNF-α-converting enzyme TNF, tumour necrosis factor Membrane Protein Secretases 56 57 58 59 60 61 Nicola, N. and Begley, C. G. (1997) Blood 90, Himmler, A., Maurer-Fogy, I., Kronke, M., Scheurich, P., Pfizenmaier, K., I,antz, M...

View article titled, Characterization of the tumour necrosis factor α-converting enzyme, TACE/ADAM17

Articles

Role for ADAM-family proteinases as membrane protein secretases

Anthony J. Turner, Nigel M. Hooper

Biochem Soc Trans (1999) 27 (2): 255–260.

https://doi.org/10.1042/bst0270255

Published: 01 February 1999

...-metalloproteinase MMP, matrix metalloproteinase PAR, proteinase-activated receptor TACE, TNF-α-converting enzyme TNF, tumour necrosis factor Membrane Protein Secretases Role for ADAM-family proteinases as membrane protein secretases Anthony J. Turner and Nigel M. Hooper School of Biochemistry and Molecular...

View article titled, Role for ADAM-family proteinases as membrane protein secretases

Articles

Interleukin-6 receptor shedding: a possible role for members of the ADAM family

P. I. Croucher, F. Wang, P. G. Hargreaves

Biochem Soc Trans (1999) 27 (2): 224–228.

https://doi.org/10.1042/bst0270224

Published: 01 February 1999

...P. I. Croucher; F. Wang; P. G. Hargreaves 1 To whom correspondence should be addressed 21 8 1998 © 1999 Biochemical Society 1999 IL, interleukin IL-6R, IL-6 receptor TIMP, tissue inhibitor of metalloproteinase TNF, tumour necrosis factor sIL-6R, soluble IL-6R...

View article titled, Interleukin-6 receptor shedding: a possible role for members of the ADAM family

Articles

Roles of ICAM-3 and CD 14 in the recognition and phagocytosis of apoptotic cells by macrophages

C. D. Gregory, A. Devitt, O. Moffatt

Biochem Soc Trans (1998) 26 (4): 644–649.

https://doi.org/10.1042/bst0260644

Published: 01 November 1998

... function-associated antigen PS, phosphatidylserine TNF, tumour necrosis factor Biochemical Society Transactions 25 26 644 Van Berkel, T. J. C., Van Velzen, A., Kruijt, J. K., Suzuki, H. and Kodama, T. (1998) Biochem. J. Terpstra, V., Kondratenko, N. and Steinberg, D. (1997) Proc. Natl. Acad. Sci...

View article titled, Roles of ICAM-3 and CD 14 in the recognition and phagocytosis of apoptotic cells by macrophages

Articles

You can lead a macrophage to an inflammatory site but can you make it eat?

S. P. Hart, A. G. Rossi, I. Dransfield

Biochem Soc Trans (1998) 26 (4): 650–652.

https://doi.org/10.1042/bst0260650

Published: 01 November 1998

...S. P. Hart; A. G. Rossi; I. Dransfield 1 To whom correspondence should be addressed. 9 7 1998 © 1998 Biochemical Society 1998 PGE 2 , prostaglandin E 2 GM-CSF, granulocyte-macrophage colony-stimulating factor IL, interleukin TNF, tumour necrosis factor TGF...

View article titled, You can lead a macrophage to an inflammatory site but can you make it eat?

Articles

Regulation of macrophage cytokine production by phagocytosis of apoptotic and post-apoptotic cells

V. A. Fadok, P. P. McDonald, D. L. Bratton, P. M. Henson

Biochem Soc Trans (1998) 26 (4): 653–656.

https://doi.org/10.1042/bst0260653

Published: 01 November 1998

..., interleukin TNF, tumour necrosis factor PS, phosphatidylserine Phagocyte Recognition of Dead and Dying Cells Regulation of macrophage cytokine production by phagocytosis of apoptotic and post-apoptotic cells V. A. Fadok', P. P. McDonald, D. L. Bratton and P. M. Henson Department of Pediatrics. National...

View article titled, Regulation of macrophage cytokine production by phagocytosis of apoptotic and post-apoptotic cells

Articles

Osteoclast differentiation and activity

G. D. Roodman

Biochem Soc Trans (1998) 26 (1): 7–13.

https://doi.org/10.1042/bst0260007

Published: 01 February 1998

..., tumour necrosis factor TGFβ, transforming growth factor-beta γ-IFN, gamma interferon OIP, osteoclast inhibitory peptide IL, interleukin PGE2, prostaglandin E 2 Molecular and Cellular Biology of the Bone IIunsberger, S. and McCowan, J. (1996) JtZM,1 276, 1389-1 396 3 Bagur, A., Wittich...

View article titled, Osteoclast differentiation and activity

Articles

Role of ceramide in tumour necrosis factor-mediated apoptosis and nuclear factor- K B activation

B. B. Aggarwal, M. Higuchi

Biochem Soc Trans (1997) 25 (4): 1166–1171.

https://doi.org/10.1042/bst0251166

Published: 01 November 1997

...]-propyloxy}benzensulphonyl) indolizine TNF, tumour necrosis factor Biochemical Society Transactions I I66 ~ Role of ceramide in tumour necrosis factor-mediated apoptosis and nuclear factor- KB activation B. B. Aggarwal' and M. Higuchi' Cytokine Research Section, Department of Molecular Oncology...

View article titled, Role of ceramide in tumour necrosis factor-mediated apoptosis and nuclear factor- K B activation

Articles

Ceramide and the eukaryotic stress response

Y. A. Hannun, L. M. Obeid

Biochem Soc Trans (1997) 25 (4): 1171–1175.

https://doi.org/10.1042/bst0251171

Published: 01 November 1997

...Y. A. Hannun; L. M. Obeid 1 To whom correspondence should be addressed 10 7 1997 © 1997 Biochemical Society 1997 NGF, nerve growth factor NF, nuclear factor PI, phosphatidylinositol PP, protein phosphatase TNF, tumour necrosis factor The Cell Biology of Lipid...

View article titled, Ceramide and the eukaryotic stress response

Articles

Xanthine oxidase: four roles for the enzyme in rheumatoid pathology

D. R. Blake, C. R. Stevens, T. Sahinoglu, G. Ellis, K. Gaffney, S. Edmonds, M. Benboubetra, R. Harrison, S. Jawed, J. Kanczler, T. M. Millar, P. G. Winyard, Z. Zhang

Biochem Soc Trans (1997) 25 (3): 812–816.

https://doi.org/10.1042/bst0250812

Published: 01 August 1997

...D. R. Blake; C. R. Stevens; T. Sahinoglu; G. Ellis; K. Gaffney; S. Edmonds; M. Benboubetra; R. Harrison; S. Jawed; J. Kanczler; T. M. Millar; P. G. Winyard; Z. Zhang 25 3 1997 © 1997 Biochemical Society 1997 ROS, reactive oxygen species TNF, tumour necrosis factor XOR, xanthine...

View article titled, Xanthine oxidase: four roles for the enzyme in rheumatoid pathology

Articles

Nitric oxide, sepsis and liver metabolism

E. D. Ceppi, F. S. Smith, M. A. Titheradge

Biochem Soc Trans (1997) 25 (3): 929–934.

https://doi.org/10.1042/bst0250929

Published: 01 August 1997

... Of multiple cytokines such as enolpyruvate carboxykinase; ROI, reactive oxygen tumour necrosis factor a (TNF-a) and inter- intermediate; TNF, tumour necrosis factor. leukin 1b (IL-1b) from the Kupffer cells and 929 I997 Biochemical Society Transactions 930 interferon y (IFN-y) from T-lymphocytes [ll-131...

View article titled, Nitric oxide, sepsis and liver metabolism

Articles

Inflammatory cytokines stimulate human biliary epithelial cells to express interleukin-8 and monocyte chemotactic protein-1

CLARE M. MORLAND, JANINE FEAR, RUTH JOPLIN, DAVID H. ADAMS

Biochem Soc Trans (1997) 25 (2): 232S.

https://doi.org/10.1042/bst025232s

Published: 01 May 1997

...CLARE M. MORLAND; JANINE FEAR; RUTH JOPLIN; DAVID H. ADAMS © 1997 Biochemical Society 1997 IL-8, interleukin-8 MCP-1, monocyte chemotactic protein-1 BEC, biliary epithilial cell TNF, tumour necrosis factor IL-1, interleukin-1 IFN, interferon TGF, transforming growth factor RT-PCR...

View article titled, Inflammatory cytokines stimulate human biliary epithelial cells to express interleukin-8 and monocyte chemotactic protein-1

Articles

Role of the double-stranded RNA-activated protein kinase (PKR) in cell regulation

B. R. G. Williams

Biochem Soc Trans (1997) 25 (2): 509–513.

https://doi.org/10.1042/bst0250509

Published: 01 May 1997

...B. R. G. Williams 20 11 1996 © 1997 Biochemical Society 1997 ds, double-stranded PKR, dsRNA-dependent protein kinase IFN, interferon TNF, tumour necrosis factor LPS, lipopoly-saccharide NFκPB, nuclear factor κPB IRF-1, regulatory factor-1 MEFs, mouse embryo fibroblasts LD...

View article titled, Role of the double-stranded RNA-activated protein kinase (PKR) in cell regulation

Articles

Haemopoietic growth factors and leukaemogenesis

A. Pierce, A. D. Whetton

Biochem Soc Trans (1997) 25 (2): 366–370.

https://doi.org/10.1042/bst0250366

Published: 01 May 1997

... factor NF1, neuro-fibromatosis SCF, stem cell factor TGF, transforming growth factor TNF, tumour necrosis factor Session 2: Signalling: 660th Meeting Joint Congress with the British Society for Immunology, held at Harrogate, 10–13 December 1996 Biochemical Society Transactions 366 4 5 6 7...

View article titled, Haemopoietic growth factors and leukaemogenesis

Articles

Microglia in health and disease

M. L. Cuzner

Biochem Soc Trans (1997) 25 (2): 671–673.

https://doi.org/10.1042/bst0250671

Published: 01 May 1997

...M. L. Cuzner 21 10 1996 © 1997 Biochemical Society 1997 IFN, interferon IL, interleukin TNF, tumour necrosis factor MBP, myelin basic protein MS, multiple sclerosis Immune Nervous Properties of Central System Parenchymal - Cells British Neuroimmunology Group Parallel...

View article titled, Microglia in health and disease

Articles

INDUCTION OF THE ADHESION MOLECULE CD44 BY THE PRO-INFLAMMATORY CYTOKINE INTERLEUKIN-1 IN ENDOTHELIAL CELLS

KATHERINE FITZGERALD, LUKE A.J. O'NEILL

Biochem Soc Trans (1997) 25 (2): 185S.

https://doi.org/10.1042/bst025185s

Published: 01 May 1997

...KATHERINE FITZGERALD; LUKE A.J. O'NEILL © 1997 Biochemical Society 1997 IL-1, interleukin-1 IL-1 RA, interleukin-1 receptor antagonist PMA, phorbol 12-meristate 13-acetate TNF, tumour necrosis factor HRP, horse radish peroxidase 660th Meeting Harrogate: 660th Meeting Joint...

View article titled, INDUCTION OF THE ADHESION MOLECULE CD44 BY THE PRO-INFLAMMATORY CYTOKINE INTERLEUKIN-1 IN ENDOTHELIAL CELLS

Articles

Cytokine regulation of matrilysin gene expression

BARBARA FINGLETON, SUSAN MCDONNELL

Biochem Soc Trans (1997) 25 (2): 155S.

https://doi.org/10.1042/bst025155s

Published: 01 May 1997

...BARBARA FINGLETON; SUSAN MCDONNELL © 1997 Biochemical Society 1997 MMP, Matrix metalloproteinase ECM, Extracellular matrix TNF, Tumour necrosis factor CM, conditioned medium IL, Interleukin IGF, Insulin-like growth factor EGF, Epidermal growth factor 660th Meeting Harrogate...

View article titled, Cytokine regulation of matrilysin gene expression

Articles

Role of natural killer and NK1 + T-cells in regulating cell-mediated immunity during Toxoplasma gondii infection

E. Y. Denkers, A. Sher

Biochem Soc Trans (1997) 25 (2): 699–703.

https://doi.org/10.1042/bst0250699

Published: 01 May 1997

...E. Y. Denkers; A. Sher ‡ To whom correspondence should be addressed. 4 11 1996 © 1997 Biochemical Society 1997 IFN, interferon IL, interleukin KO, knockout mAB, monoclonal antibody NK, natural killer TGF, transforming growth factor TNF, tumour necrosis factor...

View article titled, Role of natural killer and NK1 + T-cells in regulating cell-mediated immunity during Toxoplasma gondii infection

Articles

CD28 co-receptor signal transduction in T-cell activation

P. J. Blair, J. L. Riley, R. G. Carroll, D. C. St. Louis, B. L. Levine, B. Saha, K. P. Lee, P. J. Perrin, D. M. Harlan, C. H. June

Biochem Soc Trans (1997) 25 (2): 651–657.

https://doi.org/10.1042/bst0250651

Published: 01 May 1997

...P. J. Blair; J. L. Riley; R. G. Carroll; D. C. St. Louis; B. L. Levine; B. Saha; K. P. Lee; P. J. Perrin; D. M. Harlan; C. H. June 6 11 1996 © 1997 Biochemical Society 1997 TCR, T-cell receptor IL, inter-leukin IFN, interferon TNF, tumour necrosis factor PI, phosphoinositol...

View article titled, CD28 co-receptor signal transduction in T-cell activation

Articles

Gene regulation by low-dose ionizing radiation in a normal human lung epithelial cell line

T. A. Robson, H. Lohrer, J. R. Bailie, D. G. Hirst, M. C. Joiner, J. E. Arrand

Biochem Soc Trans (1997) 25 (1): 335–342.

https://doi.org/10.1042/bst0250335

Published: 01 February 1997

...(A) + , polyadenylated TNF, tumour necrosis factor DNA Damage and Mutagenesis 13 King, C. M., Gillespie, E. S., McKenna, P. G. and Barnett, Y. A. (1994) Mutat. Res. 316, 79-90 14 Chetsanga, C. J., Tuttle, J., Jacoboni, A. and Johnson, C. (1977) Biochim. Biophys. Acta 474, 15 Mullaart, E., Boerrigter, M. E. T. I...

View article titled, Gene regulation by low-dose ionizing radiation in a normal human lung epithelial cell line

Articles

VITAMIN C INHIBITS NFκB ACTIVATION IN ENDOTHELIAL CELLS

ANDREW BOWIE, LUKE A. J. O'NEILL

Biochem Soc Trans (1997) 25 (1): 131S.

https://doi.org/10.1042/bst025131s

Published: 01 February 1997

..., desferrioxamine; DMPO, 5,5'-dimethyl- 1-pymlinoN-oxide; H2&, h drogen peroxide; IL1, interleulun- 1; NAC, N-acetyl cysteine; PLTC, pyrrolidine dithiocarbamate; ROS, reactive oxygen species; TNF, tumour necrosis factor. previously [3]. Speci 7 IC NFKB - DNA complexes are shown. The slower H 2 Q - mediated...

View article titled, VITAMIN C INHIBITS NFκB ACTIVATION IN ENDOTHELIAL CELLS

Articles

Molecular Mechanisms Underlying the Actions of the Pro-inflammatory Cytokine Interleukin I

L. A. J. O'Neill

Biochem Soc Trans (1997) 25 (1): 295–302.

https://doi.org/10.1042/bst0250295

Published: 01 February 1997

...L. A. J. O'Neill 15 8 1996 © 1997 Biochemical Society 1997 IL, interleukin IL1RA, IL1 receptor antagonist IL1RI, type I IL1 receptor IL1RII, type II IL1 receptor MAP, mitogen-activated protein NFκB, nuclear factor κB TNF, tumour necrosis factor Molecular Mechanisms...

View article titled, Molecular Mechanisms Underlying the Actions of the Pro-inflammatory Cytokine Interleukin I

Articles

Apoptosis as a trigger of inflammation in Shigella -induced cell death

A. Guichon, A. Zychlinsky

Biochem Soc Trans (1996) 24 (4): 1051–1054.

https://doi.org/10.1042/bst0241051

Published: 01 November 1996

...- morphonuclear; +a, invasion plasmid antigen; GST, glutathione S-transferase; ICE, IL-18-converting enzyme; TNF, tumour necrosis factor; IL-lra, IL-1 receptor antagonist. *To whom correspondence should be addressed. PMN cells may account for limiting the spread of the micro-organism and resolving the infection...

View article titled, Apoptosis as a trigger of inflammation in Shigella -induced cell death

Articles

Cell death signal transduction and Bcl-2 function

J. L. Herrmann, E. Bruckheimer, T. J. McDonnell

Biochem Soc Trans (1996) 24 (4): 1059–1065.

https://doi.org/10.1042/bst0241059

Published: 01 November 1996

...J. L. Herrmann; E. Bruckheimer; T. J. McDonnell * To whom correspondence should be addressed. 20 5 1996 © 1996 Biochemical Society 1996 TNF, tumour necrosis factor ICE, interleukin-1β-converting enzyme ROS, reactive oxygen species NF, nuclear factor SV, Sinbis virus...

View article titled, Cell death signal transduction and Bcl-2 function

Articles

Dithiocarbamates and the redox regulation of cell death

S. Orrenius, C. S. I. Nobel, D. J. van den Dobbelsteen, M. J. Burkitt, A. F. G. Slater

Biochem Soc Trans (1996) 24 (4): 1032–1038.

https://doi.org/10.1042/bst0241032

Published: 01 November 1996

..., pyrrolidine dithiocarbamate DSF, disulphiram FCS, foetal calf serum TNF, tumour necrosis factor Biochemical Society Transactions I032 16 17 18 19 20 21 22 Dupont, G. P., IIuecksteadt, T. P., Marshall, B. C., Ryan, U. S., Michael, J. R. and Iloidal, J. R. (1992) J. Clin. Invest. 89, 197-202 Burdon, R. H...

View article titled, Dithiocarbamates and the redox regulation of cell death

Articles

Immunological manipulation of adiposity

D. J. Flint

Biochem Soc Trans (1996) 24 (2): 418–422.

https://doi.org/10.1042/bst0240418

Published: 01 May 1996

...D. J. Flint 17 11 1995 © 1996 Biochemical Society 1996 CDR, complementarity-determining region LPL, lipoprotein lipase TNF, tumour necrosis factor Biochemical Society Transactions 418 33 Carpene, C., Castan, I., Collon, P., Galitzky, J., Moratinos, J. and Lafontan, M. (1994...

View article titled, Immunological manipulation of adiposity

Articles

Mechanism of NFκB activation by interleukin-1 and tumour necrosis factor in endothelial cells

Andrew Bowie, Paul N. Moynagh, Luke A.J. O'neill

Biochem Soc Trans (1996) 24 (1): 2S.

https://doi.org/10.1042/bst024002s

Published: 01 February 1996

...Andrew Bowie; Paul N. Moynagh; Luke A.J. O'neill © 1996 Biochemical Society 1996 EC, endothelial cell IL1, interleukin-1 NAC, N-acetyl cysteine PDTC, pyrrolidine dithiocarbamate PMA, phorbol 12-myristate 13-acetate ROS, reactive oxygen species TNF, tumour necrosis factor...

View article titled, Mechanism of NFκB activation by interleukin-1 and tumour necrosis factor in endothelial cells

Articles

Can n — 3 polyunsaturated fatty acids be used as immunomodulatory agents?

P. C. Calder

Biochem Soc Trans (1996) 24 (1): 211–220.

https://doi.org/10.1042/bst0240211

Published: 01 February 1996

..., natural killer cells PBL, peripheral blood lymphocyte PC, phosphatidylcholine PG, prostaglandin PIP 2 , phosphatidylinositol 4,5-bisphosphate PKC, protein kinase C PS, phosphatidylserine PUFA, polyunsaturated fatty acid TAG, triacylglycerol TNF, tumour necrosis factor TX, thromboxane...

View article titled, Can n — 3 polyunsaturated fatty acids be used as immunomodulatory agents?

Articles

Effects of endotoxin on lipid metabolism

I. Hardardóttir, C. Grunfeld, K. R. Feingold

Biochem Soc Trans (1995) 23 (4): 1013–1018.

https://doi.org/10.1042/bst0231013

Published: 01 November 1995

..., lecithin:cholesterol acyltransferase LDL, low-density lipoprotein LPL, lipoprotein lipase SAA, serum amyloid A TNF, tumour necrosis factor VLDL, very-lowdensity lipoprotein Endotoxic Shock and Metabolism 44 45 46 47 (1992) J. Leukocyte Biol. 52, 390-394 Billiar, T . R., Curran, R. D., Harbrecht, B. G., Stuehr...

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P.-O. Hasselgren

Biochem Soc Trans (1995) 23 (4): 1019–1025.

https://doi.org/10.1042/bst0231019

Published: 01 November 1995

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Clinical trials with CAMPATH-I and other monoclonal antibodies

G. Hale, J. M. Phillips

Biochem Soc Trans (1995) 23 (4): 1057–1063.

https://doi.org/10.1042/bst0231057

Published: 01 November 1995

...G. Hale; J. M. Phillips * To whom correspondence should be addressed. 26 6 1995 © 1995 Biochemical Society 1995 ADCC, antibody-dependent cellmediated cytotoxicity GPI, glycosylphosphatidylinositol TNF, tumour necrosis factor Therapeutic Monoclonals 1766- 1774 4...

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A. Ray, D.-H. Zhang, P. Ray

Biochem Soc Trans (1995) 23 (4): 952–958.

https://doi.org/10.1042/bst0230952

Published: 01 November 1995

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Bacterial endotoxin effects on carbohydrate utilization and transport

J. J. Spitzer

Biochem Soc Trans (1995) 23 (4): 998–1002.

https://doi.org/10.1042/bst0230998

Published: 01 November 1995

...J. J. Spitzer 19 6 1995 © 1995 Biochemical Society 1995 LPS, lipopolysaccharide PMN, polymorphonuclear leucocyte Rd, total body glucose uptake Rg, glucose uptake by a tissue TNF, tumour necrosis factor Biochemical Society Transactions 13 Feder, L. S. and Laskin, D. L...

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Mechanism of inhibition of hepatic gluconeogenesis by bacterial endotoxin: a role for nitric oxide?

M. A. Titheradge, R. G. Knowles, F. S. Smith, R. A. Horton, E. D. Ceppi

Biochem Soc Trans (1995) 23 (4): 1002–1008.

https://doi.org/10.1042/bst0231002

Published: 01 November 1995

..., lipopolysaccharide NO, nitric oxide PEP, phosphoenolpyruvate PEPCK, phosphoenolpyruvate carboxykinase SNAP, S-nitroso- N -acetylpenicillamine TNF, tumour necrosis factor Biochemical Society Transactions H., MCsziros, K., and Spitzer, J. J. (1991) J. Leukocyte Biol. 49, 309-312 21 Spolarics, Z., Bautista...

View article titled, Mechanism of inhibition of hepatic gluconeogenesis by bacterial endotoxin: a role for nitric oxide?

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