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Keywords: T cell development
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Biochem Soc Trans (2021) 49 (5): 2113–2122.
Published: 13 October 2021
... as a valid read-out. Several in vitro models of T cell development have been established which are able to induce T-lineage differentiation from different hematopoietic precursors, although with variable efficiency. Here, we review the potential of human HSCs from various sources to generate T-lineage cells...