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Keywords: Srs2 helicaseClose
Journal: Biochemical Society Transactions
Biochem Soc Trans (2005) 33 (6): 1447–1450.
Published: 26 October 2005
... and sometimes cell death. Genetic analyses in the yeast Saccharomyces cerevisiae have revealed a central role of the Srs2 helicase in preventing untimely HR events and in inhibiting the formation of potentially deleterious DNA structures or nucleoprotein complexes upon DNA replication stress. Paradoxically...