... even uncovered circumstances where their thioredoxin peroxidase activity is detrimental. In the present paper, we focus on what we have learned from studies in the fission yeast Schizosaccharomyces pombe about the different roles of 2-Cys Prxs in responses to H 2 O 2 and discuss the general...

... centromere chromosome heterochromatin fission yeast loss of heterozygosity (LOH) recombination Schizosaccharomyces pombe Swi6 Certain cancer cells, particularly solid tumours, are known for dramatic CIN (chromosome instability) phenotypes. Aneuploidy and other numerical disruptions (nCIN...

... Biochemical Society 2013 cell division cycle 25 (Cdc25) centrosome mitosis Polo kinase Schizosaccharomyces pombe Wee1 Figure 1 Cdk1–cyclin B control ( A ) Phosphorylation by Wee1 kinase of Cdk1 on Thr 14 and Tyr 15 within its ATP-binding pocket blocks the activity of the complex...

...Ana Santos de Medeiros; Alexander Magee; Kyle Nelson; Liora Friedberg; Karolina Trocka; Charles S. Hoffman PKA (protein kinase A) in the fission yeast Schizosaccharomyces pombe controls transcription of genes involved in metabolism, cell growth and sexual development. In the present review, we...

.... The recent availability of overexpression and deletion strains for almost all of the transcription factor genes in the fission yeast Schizosaccharomyces pombe provides a valuable resource to better investigate transcription factors using systematic genetics. In the present paper, I review and discuss...

... compilation © 2008 Biochemical Society 2008 Cds1 minichromosome maintentance (MCM) Mrc1 Rad51 Rad53 Rhp51 Schizosaccharomyces pombe The MCM proteins are a family of highly conserved AAA (ATPase associated with various cellular activities) proteins that form a heterohexameric protein...

... conjugation of SUMO to proteins can occur in the absence of a SUMO ligase, it is apparent that SUMO ligases facilitate the SUMOylation of specific subsets of proteins. Two SUMO ligases in Schizosaccharomyces pombe , Pli1 and Nse2, have been identified, both of which have roles in genome stability. We report...

...C.S. Hoffman The fission yeast Schizosaccharomyces pombe primarily detects glucose via a cAMP-signalling pathway. Components of this pathway include the Git3 G-protein-coupled receptor and a heterotrimeric G-protein, from which the Gpa2 Gα subunit activates adenylate cyclase (Git2/Cyr1). Three...