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Biochem Soc Trans (2021) 49 (6): 2879–2890.
Published: 02 December 2021
...Kensaku Murano; Youjia Guo; Haruhiko Siomi The novel coronavirus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the cause of the coronavirus disease (COVID-19) pandemic. As of August 2021, more than 200 million people have been infected with the virus and 4.3 million have lost...
Biochem Soc Trans (2021) 49 (1): 281–295.
Published: 13 January 2021
... recently, SARS-CoV-2 (COVID-19). Ivermectin has thus far been tested in Phase III human clinical trials for DENV, while there are currently close to 80 trials in progress worldwide for SARS-CoV-2; preliminary results for randomised clinical trials (RCTs) as well as observational/retrospective studies...
Biochem Soc Trans (2022) 50 (1): 151–165.
Published: 11 January 2021
...Anoop Narayanan; Shay A. Toner; Joyce Jose SARS-CoV-2, the coronavirus responsible for the current COVID-19 pandemic, encodes two proteases, 3CL pro and PL pro , two of the main antiviral research targets. Here we provide an overview of the structures and functions of 3CL pro and PL pro and examine...
Biochem Soc Trans (2021) 49 (1): 341–352.
Published: 24 December 2020
... of the most recent discoveries made possible by analyses of the SARS-CoV-2 genome. Correspondence: Danny Incarnato ( email@example.com ) 6 11 2020 8 12 2020 10 12 2020 © 2020 The Author(s) 2020 This is an open access article published by Portland Press Limited on behalf...
Biochem Soc Trans (2020) 48 (6): 2625–2641.
Published: 01 December 2020
...Dene R. Littler; Bruce J. MacLachlan; Gabrielle M. Watson; Julian P. Vivian; Benjamin S. Gully The race to identify a successful treatment for COVID19 will be defined by fundamental research into the replication cycle of the SARS-CoV-2 virus. This has identified five distinct stages from which...
Biochem Soc Trans (2020) 48 (6): 2851–2863.
Published: 10 November 2020
...Jiayue-Clara Jiang; Yan Zhang The ongoing COVID-19 pandemic has placed an overwhelming burden on the healthcare system, and caused major disruption to the world economy. COVID-19 is caused by SARS-CoV-2, a novel coronavirus that leads to a variety of symptoms in humans, including cough, fever...
Zhongyi Wang, Yingying Fu, Zhendong Guo, Jiaming Li, Jingjing Li, Hongliang Cheng, Bing Lu, Qiang Sun
Biochem Soc Trans (2020) 48 (5): 2307–2316.
Published: 21 October 2020
...Zhongyi Wang; Yingying Fu; Zhendong Guo; Jiaming Li; Jingjing Li; Hongliang Cheng; Bing Lu; Qiang Sun The coronavirus disease 2019 (COVID-19), caused by a novel virus of the β-coronavirus genus (SARS-CoV-2), has been spreading globally. As of July 2020, there have been more than 17 million cases...
Biochem Soc Trans (2020) 48 (3): 1287–1295.
Published: 08 June 2020
...Spencer J. Williams; Ethan D. Goddard-Borger The ongoing COVID-19 pandemic, caused by SARS-CoV-2, has pushed the health systems of many countries to breaking point and precipitated social distancing measures that have crippled economic activities across the globe. A return to normality is unlikely...