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Keywords: RhoGAP
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Articles

A PLCδ 1 -binding protein, p122RhoGAP, is localized in focal adhesions

K. Kawai, M. Yamaga, Y. Iwamae, M. Kiyota, H. Kamata, H. Hirata, Y. Homma, H. Yagisawa
Journal: Biochemical Society Transactions
Biochem Soc Trans (2004) 32 (6): 1107–1109.
DOI: https://doi.org/10.1042/BST0321107
Published: 26 October 2004
... The Biochemical Society 2004 actin cytoskeleton focal adhesion phospholipase C RhoGAP tumour suppressor vinculin p122RhoGAP (p122) (where GAP stands for GTPase-activating protein) is a dual functional molecule. It was cloned from a rat cDNA library and demonstrated to interact with PLCδ 1...
View article titled, A PLCδ 1 -binding protein, p122RhoGAP, is localized in focal adhesions
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Articles

Filling the GAPs in cell dynamics control: BPGAP1 promotes cortactin translocation to the cell periphery for enhanced cell migration

B.L. Lua, B.C. Low
Journal: Biochemical Society Transactions
Biochem Soc Trans (2004) 32 (6): 1110–1112.
DOI: https://doi.org/10.1042/BST0321110
Published: 26 October 2004
... largely remain unknown. BPGAP1 is a novel RhoGAP that co-ordinately regulates pseudopodia and cell migration through the interplay of its BNIP-2 and Cdc42GAP homology domains serving as a homophilic/heterophilic interaction device, an enzymic RhoGAP domain that inactivates RhoA and a proline-rich region...
View article titled, Filling the GAPs in cell dynamics control: BPGAP1 promotes cortactin translocation to the cell periphery for enhanced cell migration
Click here to open pdf in another window PDF for Filling the GAPs in cell dynamics control: BPGAP1 promotes cortactin translocation to the cell periphery for enhanced cell migration