... processes related to cytoskeletal dynamics, polarity and gene transcription. In the last decade, major new advances have been made in understanding the regulatory role and mechanism of Rho GTPases in self-renewal, differentiation, migration, and lineage specification in tissue-specific signaling mechanisms...

... pilot with Portland Press and the Biochemical Society under a transformative agreement with JISC. cancer Cdc42 metastasis Rho GTPases Table 3 Percentage alterations for 25 RhoGAPs with Cdc42 activity across multiple cancer types from cBioPortal, TCGA datasets, Accessed March 2021...

...Victoria Casado-Medrano; Martin J. Baker; Cynthia Lopez-Haber; Mariana Cooke; Shaofei Wang; Maria J. Caloca; Marcelo G. Kazanietz The family of Rho GTPases are involved in the dynamic control of cytoskeleton reorganization and other fundamental cellular functions, including growth, motility...

...Aaron J. Farrugia; Fernando Calvo Despite being discovered more than 15 years ago, the Borg (binder of Rho GTPases) family of Cdc42 effector proteins (Cdc42EP1–5) remains largely uncharacterised and relatively little is known about their structure, regulation and role in development and disease...