... response of murine mammary tumours in which the secretion of exosomes was inhibited or not. A 50% decrease in exosome secretion was obtained by the abolition of Rab27a expression in two mouse mammary carcinoma cells that were then injected subcutaneously in immunocompetent mice [ 19 ]. In the 4T1 model...

... paper, we review the evidence supporting the proposed mechanisms of Rab targeting and highlight insights into this process provided by studies of Rab27a. melanocyte melanosomes Rab27a Rab GTPase Rab27 is thought to play diverse roles in different cell types through interacting...